Yun-kyung Song

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In this study, we investigated the effect of acupuncture at the Zusanli acupoint (ST36) on the nigrostriatal dopaminergic neuronal cell death in the rats with Parkinson's disease. Two weeks after unilateral injection of 6-hydroxydopamine (6-OHDA) into the striatum, an apomorphine-induced rotational behavior test showed significant rotational asymmetry in(More)
BACKGROUND Obesity, which is described as excessive or abnormal body fat, increases the risk of diet-related diseases. In Korea and around the world, the prevalence of obesity has grown annually from 1998 to 2008. This growth has continued despite various therapeutic efforts. The discovery of new and alternative treatments for obesity should be considered(More)
Herbal prescription, Danggui-Sayuk-Ga-Osuyu-Saenggang-tang (DSGOST), has long been used to treat Raynaud's phenomenon (RP) in traditional Chinese medicine (TCM). However, a biological mechanism by which DSGOST ameliorates RP is yet deciphered. In this study, we demonstrate that DSGOST inhibits cold-induced activation of RhoA, in both vascular smooth muscle(More)
Background. Obesity is associated with chronic inflammation and cytokines. However, to date, the relationship between the serum levels of cytokines in obese individuals and taking herbal drugs remains largely unexplored. Methods. Serum cytokines were assessed by multiplex cytokine profiling assay. Serum samples of obese female Korean adults (obese group; n(More)
Objective. The aim of this systematic review is to evaluate the efficacy and safety of herbal medicines in the management of metabolic syndrome. Materials and Methods. On December 9, 2015, we searched PubMed, EMBASE, Cochrane Library, SCOPUS, AMED, CNKI, KoreaMed, KMBASE, OASIS, and J-STAGE with no restriction on language or published year. We selected(More)
BACKGROUND Obesity has become a major global health challenge due to its increasing prevalence, and the associated health risk. It is the main cause of various metabolic diseases including diabetes, hypertension, cardiovascular disease, stroke and certain forms of cancer. METHODS AND RESULTS In the present study we evaluated the anti-obesity property of(More)
Objective. The purpose of this study was to assess the efficacy and safety of Taeeumjowi-tang (TJ001) as well as to estimate obesity-related factors. Methods. This was a 12-week trial with 5 visits. A total of 102 participants of both genders were randomized to either TJ001 (n = 57) group or the placebo group (n = 55). Subjects were administered 7 g of(More)
Acupuncture has been widely used for pain control. However, the mechanism of pain inhibition by acupuncture is still unclear and evaluation of the physiological effects of acupuncture is limited 1,2). Many studies have indicated that objective physiological measurements are associated with the determination of the effects of acupuncture. Physiological(More)
Introduction Peripheral nerve systems are often damaged by crush, compression, ischemia and various diseases. In the sciatic crushed nerve injury, the injured limb displays hyperalgesia, pain-related gait and swelling 1). These features are abnormal responses to peripheral stimuli and they induce changes of secretion and neural transmission. In peripheral(More)
Introduction Peripheral nerves are frequently exposed to physical injury and this can result in a severe functional impairment and decreased quality of life, because it sometimes induces loss of sensory and motor functions. Crush injury to the sciatic nerve has been used as the animal model of unilateral peripheral neuro-pathy. Many changes affecting the(More)