Yun-Qian Zhang

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BACKGROUND & AIMS Fibrotic changes seem to be responsible for the high mortality rate observed in patients with acute respiratory distress syndrome (ARDS). The present study aimed to determine whether resveratrol, a natural antioxidant polyphenol, had anti-fibrotic effects in the murine model of lipopolysaccharide (LPS)-induced pulmonary fibrosis. METHODS(More)
BACKGROUND Resveratrol, a natural plant polyphenol, has received increasing attention because its varied bioactivities, including the inhibition of tumorigenesis, lipid modification and calorie-restriction. We aimed to investigate the effect of resveratrol on oxidative/nitrative stress in endotoxemia-associated acute lung injury. METHODS Mice were(More)
To explore differences in coordination between alkali- and alkaline-earth-metal ions and cucurbit[n]urils, a water-soluble α,α',δ,δ'-tetramethylcucurbit[6]uril (TMeQ[6]) was used to synthesize a series of complexes and their supramolecular assemblies, based on the coordination of TMeQ[6] with alkali- and alkaline-earth-metal ions. The complexes and(More)
There is intensive interest in the design of tubular channels because of their novel structures and various applications in a variety of research fields. Herein, we present a series of coordination-driven Q[7]-derived organic nanochannels using an anion-induced strategy under different acid concentrations. An advantage of this approach is that the tubular(More)
In the present study, we introduce the coordination of samarium-Q[5] systems in the absence and presence of the third species, and the corresponding supramolecular assemblies are dependent upon the addition of the third species. In the absence of the third species, a samarium cation (nitrate salt) coordinates to a Q[5] molecule and forms a molecular bowl;(More)
In the title compound, C 10 H 12 N 8 O 4 ÁH 2 O, prepared from the reaction of glycoluril with paraformaldehyde, the organic molecule has mm symmetry. The asymmetric unit comprises one quarter of the molecule and a half-molecule of water. The dimer is formed by bridging two glycoluril molecules with methylene groups at the 1 and 6 positions. In the crystal(More)
The asymmetric unit of the title compound, (C(24)H(26)N(2))[ZnCl(4)], consists of two 2,2'-(hexane-1,6-di-yl)diisoquinolinium cations and two [ZnCl(4)](2-) complex anions. The [ZnCl(4)](2-) anions have a distorted tetra-hedral geometry. The dihedral angles between the isoquinoline rings of the two cations are nearly equal [16.1 (2) and 16.3 (2)°]. In the(More)
In the crystal structure of the title compound, C(13)H(11)N(4)O(3) (+)·Cl(-), the dihedral angle between the two pyridine rings is 9.72 (9) Å. Ions are linked via N-H⋯Cl, O-H⋯Cl and O-H⋯O hydrogen bonds, forming a three-dimensional framework.
Complexation of cyclohexanocucurbit[6]uril (Q*[6]), a water-soluble cucurbit[n]uril derivative, with Cd(2+) ions has been studied by means of cyclic voltammetry and differential pulse voltammetry. The electrochemical experimental data prove the formation of a highly stable 1:6 Q*[6]/Cd(2+) complex. We also obtained the single-crystal X-ray structure of a(More)