Yun Pan

Learn More
Certain pseudogenes may regulate their protein-coding cousins by competing for miRNAs and play an active biological role in cancer. However, few studies have focused on the association of genetic variations in pseudogenes with cancer prognosis. We selected six potentially functional single nucleotide polymorphisms (SNPs) in cancer-related pseudogenes, and(More)
In this paper, a hierarchical resampling (HR) architecture has been presented for distributed particle filters (PFs). The proposed archi-tectures decomposes the resampling step into two hierarchies, of which the first one, called intermediate resampling, is conducted consecutively among processing elements (PEs) the moment new particles and their weights(More)
The network-on-chip (NoC) architecture is a main factor affecting the system performance of complicated multi-processor systems-on-chips (MPSoCs). To evaluate the effects of the NoC architectures on communication efficiency, several kinds of techniques have been developed, including various simulators and analytical models. The simulators are accurate but(More)
BACKGROUND Skin cancer is the most common cancer in the United States, and ultraviolet B (UVB) radiation-induced DNA damage is the major environmental factor underlying skin cancer development. p21, a p53-inducible protein, plays a key role in the cellular response to UVB-induced DNA damage. MATERIAL AND METHODS Through p21 silencing and overexpression,(More)
BACKGROUND MiR-106b-25 cluster, hosted in intron 13 of MCM7, may play integral roles in diverse processes including immune response, tumorigenesis and progression. A single nucleotide polymorphism (SNP), rs999885, is located in the promoter region of MCM7. Our previous study showed that the A to G base change of rs999885 may provide an increased risk for(More)