Yun-Lung Ho

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A focused library of furanopyrimidine (350 compounds) was rapidly synthesized in parallel reactors and in situ screened for Aurora and epidermal growth factor receptor (EGFR) kinase activity, leading to the identification of some interesting hits. On the basis of structural biology observations, the hit 1a was modified to better fit the back pocket,(More)
The water-soluble Roussin's red ester [(NO)(2)Fe(mu-SCH(2)CH(2)P(O)(CH(2)OH)(2))(2)Fe(NO)(2)] (1), a potential photochemical prodrug of an NO precursor, was synthesized from the reaction of HSCH(2)CH(2)P(O)(CH(2)OH)(2) (F) and [Fe(CO)(2)(NO)(2)]. The IR v(NO) stretching frequencies of complex 1 appear at 1759 (s), 1784 (s) and 1816 (w) cm(-1) in buffer (pH(More)
In this paper we will report a novel CMP slurry chemistry which can provide tunable removal selectivity between various silicon-containing materials, such as SiGe, bare silicon, poly silicon or amorphous silicon against SiO<sub>2</sub> and/or SiN. The slurry chemistry is a non-hydrogen peroxide based system containing a novel catalyst. By adjusting the(More)
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