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Positively-charged gold nanoparticles possess intrinsic peroxidase-like activity, and can catalyze oxidation of the peroxidase substrate 3,3,5,5-tetramethylbenzidine (TMB) by H(2)O(2) to develop a blue color in aqueous solution, thus providing a simple approach to colorimetric detection of H(2)O(2) and glucose.
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