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  • J. Choi, D. Herr, +8 authors J. Chun
  • Medicine, Biology
  • Annual review of pharmacology and toxicology
  • 2010 (First Publication: 6 January 2010)
  • Lysophosphatidic acid (LPA) is a small, ubiquitous phospholipid that acts as an extracellular signaling molecule by binding to and activating at least five known G protein-coupled receptors (GPCRs):Expand
  • J. Choi, S. Gardell, +8 authors J. Chun
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 2010 (First Publication: 21 December 2010)
  • Sphingosine 1-phosphate (S1P), a lysophospholipid, has gained relevance to multiple sclerosis through the discovery of FTY720 (fingolimod), recently approved as an oral treatment for relapsing formsExpand