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We describe here a multiplexed protein quantitation strategy that provides relative and absolute measurements of proteins in complex mixtures. At the core of this methodology is a multiplexed set of isobaric reagents that yield amine-derivatized peptides. The derivatized peptides are indistinguishable in MS, but exhibit intense low-mass MS/MS signature ions(More)
BACKGROUND Human embryonic stem cell (hESC) lines derived from poor quality embryos usually have either normal or abnormal karyotypes. However, it is still unclear whether their biological characteristics are similar. METHODS Seven new hESC lines were established using discarded embryos. Five cell lines had normal karyotype, one was with an unbalanced(More)
This paper is concerned with the infinite horizon linear quadratic (LQ) optimal control for discrete-time stochastic systems with both state and control-dependent noise. Under assumptions of stabilization and exact observability, it is shown that the optimal control law and optimal value exist, and the properties of the associated discrete algebraic Riccati(More)
To investigate the potential role of SOX2 in gastric cancer (GC) metastasis. The SOX2 expression was detected using immunohistochemistry on a GC tissue microarray. The correlations of SOX2 expression with clinicopathological factors and 5-year survival were evaluated. To test the role of SOX2 in inhibiting GC metastasis, the cell transwell assay was(More)
Heavy metals have significant negative effects on anoxic/aerobic-membrane bioreactors (A/O-MBR). The changes in the performance of A/O-MBR fed with municipal wastewater containing 0.25-2.56 mg/L (low concentrations) and 3.7-32.3mg/L (high concentrations) of zinc, copper, lead, and cadmium were studied in this paper. The nitrification rate decreased to 27%(More)
With appropriate geometry configurations, bistatic synthetic aperture radar (SAR) can break through the limitations of monostatic SAR on forward-looking imaging. Thanks to such a capability, bistatic forward-looking SAR (BFSAR) has extensive potential applications, such as self-navigation and self-landing. In the mode of BFSAR with a stationary transmitter(More)
The generation of patient-specific nuclear transfer embryonic stem cells holds huge promise in modern regenerative medicine and cell-based drug discovery. Since human in vivo matured oocytes are not readily available, human therapeutic cloning is developing slowly. Here, we investigated for the first time whether human polyspermic zygotes could support(More)
This paper presents a parameterized parallel Turbo decoder for 3GPP LTE terminals. To support the high peak data-rate defined in the forthcoming 3GPP LTE standard, Turbo decoder with a throughout beyond 150Mbit/s is needed as a key component of the radio baseband chip. By exploiting the tradeoff of precision, speed and area consumption, a Turbo decoder with(More)