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Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration.
Biodistribution experiment showed that TiO(2) mainly retained in the liver, spleen, kidneys, and lung tissues, which indicated thatTiO( 2) particles could be transported to other tissues and organs after uptake by gastrointestinal tract. Expand
Acute toxicological effects of copper nanoparticles in vivo.
Results indicate a gender dependent feature of nanotoxicity andKidney, liver and spleen are found to be target organs of nano-copper particles. Expand
Cytotoxicity of carbon nanomaterials: single-wall nanotube, multi-wall nanotube, and fullerene.
Carbon nanomaterials with different geometric structures exhibit quite different cytotoxicity and bioactivity in vitro, although they may not be accurately reflected in the comparative toxicity in vivo. Expand
Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO(2) nanoparticles.
Rutile ultrafine-TiO(2) particles are expected to have a little lower risk potential for producing adverse effects on central nervous system, although understanding the mechanisms requires further investigation, the present results suggest that the authors should pay attention to potential risk of occupational exposure for large-scaled production of TiO( 2) nanoparticles. Expand
Toxicity of zinc oxide nanoparticles to zebrafish embryo: a physicochemical study of toxicity mechanism
The biological impact of engineered nanomaterials released into the aquatic environment is a major concern. In this work, the properties of ZnO nanoparticles (nano-ZnO, 30 nm) were characterized in aExpand
Cellular uptake, intracellular trafficking, and cytotoxicity of nanomaterials.
This article focusses on the cellular uptake, location and translocation, and any biological consequences, such as cytotoxicity, of the most widely studied and used nanoparticles,such as carbon-based nanoparticle, metallic nanoparticles and quantum dots. Expand
Potential neurological lesion after nasal instillation of TiO(2) nanoparticles in the anatase and rutile crystal phases.
Results provided the preliminary evidence that nasal instilled TiO(2) nanoparticles could be translocated into the central nervous system and cause potential lesion of brain, and the hippocampus would be the main target within brain. Expand
Effects of rare earth oxide nanoparticles on root elongation of plants.
The phytotoxicity of four rare earth oxide nanoparticles on seven higher plant species and their effects on root growth varied greatly between different nanoparticles and plant species are investigated by means of root elongation experiments. Expand
Binding of blood proteins to carbon nanotubes reduces cytotoxicity
Light is shed toward the design of safe carbon nanotube nanomaterials by comprehensive preconsideration of their interactions with human serum proteins by finding a competitive binding of these proteins with different adsorption capacity and packing modes. Expand
Acute toxicological impact of nano- and submicro-scaled zinc oxide powder on healthy adult mice
In this work, the acute oral toxicity of 20- and 120-nm ZnO powder at doses of 1-, 2-, 3-, 4-, 5-g/kg body weight was evaluated referred to the OECD guidelines for testing of chemicals. As theExpand