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Transcriptional regulation of the CADM1 gene by retinoic acid during the neural differentiation of murine embryonal carcinoma P19 cells
It is suggested that Sp1 plays a critical role in RA‐induced CADM1 expression through possible interaction with RARα in the neural differentiation of P19 and the suppression of CADm1 expression using RNAi interfered with P19 cell aggregation and reduced cell populations expressing MAP2 after RA treatment.