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Plasma LDL and HDL cholesterol and oxidized LDL concentrations are altered in normo- and hypercholesterolemic humans after intake of different levels of cocoa powder.
Cocoa powder is rich in polyphenols, such as catechins and procyanidins, and has been shown in a variety of subject models to inhibit oxidized LDL and atherogenesis. Our study evaluated plasma LDL… Expand
Type of cell death induced by seven metals in cultured mouse osteoblastic cells.
- R. Contreras, José Rogelio Scougall Vilchis, +5 authors J. Shimada
- Biology, Medicine
- In vivo
- 1 July 2010
The use of dental metal alloys in the daily clinic makes it necessary to evaluate the cytotoxicity of eluted metal components against oral cells. However, the cytotoxic mechanism and the type of cell… Expand
Comparative assessment of distribution of blackcurrant anthocyanins in rabbit and rat ocular tissues.
- H. Matsumoto, Yuko Nakamura, H. Iida, Kyoko Ito, H. Ohguro
- Medicine, Chemistry
- Experimental eye research
- 1 August 2006
Anthocyanins (ACs) are phenolic compounds that are distributed widely in fruits and vegetables. Although consumption of these compounds has been shown to improve visual function, the distribution of… Expand
Endothelium-dependent vasorelaxation induced by black currant concentrate in rat thoracic aorta.
We investigated the effect of black currant (BC) concentrate on smooth muscle in rat thoracic aorta. BC concentrate dose-dependently relaxed the norepinephrine (0.1 microM)-precontracted aorta, and… Expand
Cacao procyanidins reduce plasma cholesterol and increase fecal steroid excretion in rats fed a high‐cholesterol diet
Cocoa powder is rich in polyphenols, such as catechins and oligomeric procyanidins, and has a hypocholesterolemic effect in humans. This study evaluated the principal active components and potential… Expand
Systematic review and meta-analysis reveals acutely elevated plasma cortisol following fasting but not less severe calorie restriction
Abstract Elevated plasma cortisol has been reported following caloric restriction, and may contribute to adverse effects including stress-induced overeating, but results from published studies are… Expand
Selective antibacterial and apoptosis-modulating activities of mastic.
Mastic is a resinous exudate obtained from the stem and the main leaves of Pistacia lentiscus. We have reported the antiplaque effect of mastic-containing chewing gum on the oral cavity. We… Expand
Development and validation of a liquid chromatography tandem mass spectrometry method for simultaneous determination of four anthocyanins in human plasma after black currant anthocyanins ingestion.
- Yuko Nakamura, H. Matsumoto, M. Morifuji, H. Iida, Y. Takeuchi
- Chemistry, Medicine
- Journal of agricultural and food chemistry
- 27 January 2010
Black currant anthocyanins consist of delphinidin-3-glucoside (1), delphinidin-3-rutinoside (2), cyanidin-3-glucoside (3), and cyanidin-3-rutinoside (4). A liquid chromatography tandem mass… Expand
Fructooligosaccharides suppress high‐fat diet‐induced fat accumulation in C57BL/6J mice
- Yuko Nakamura, M. Natsume, Akiko Yasuda, M. Ishizaka, Keiko Kawahata, Jinichiro Koga
- Biology, Medicine
- 1 March 2017
Two experiments were performed to examine the effects of fructooligosaccharides (FOS) on the development of obesity. In the first experiment, Wistar rats were orally administered a 2.5 g/kg body… Expand
Hormetic and anti-radiation effects of tropolone-related compounds.
We have previously investigated a total of 173 azulene-, tropolone- and azulenequinone-related compounds for their tumor-specificity and anti-inflammatory activity. In this study, we selected six… Expand