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Abundance of Prereplicative Complexes (Pre-RCs) Facilitates Recombinational Repair under Replication Stress in Fission Yeast*
Background: Assembly of many prereplicative complexes (pre-RCs) is important for DNA replication and surviving replication stress. Results: A reduction of pre-RCs caused accumulation of Rhp54/Rad54Expand
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Identification and characterization of GSRP-56, a novel Golgi-localized spectrin repeat-containing protein.
Spectrin repeat (SR)-containing proteins are important for regulation of integrity of biomembranes, not only the plasma membrane but also those of intracellular organelles, such as the Golgi,Expand
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Suppression of allergic and inflammatory responses by essential oils derived from herbal plants and citrus fruits.
The aim of the present study was to investigate the biological activity of 20 essential oils (EOs) derived from herbal plants and citrus fruits. The in vitro anti-allergic and anti-inflammatoryExpand
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Calcineurin Inhibits Na+/Ca2+ Exchange in Phenylephrine-treated Hypertrophic Cardiomyocytes*
The cardiac Na+/Ca2+ exchanger (NCX1) is the predominant mechanism for the extrusion of Ca2+ from beating cardiomyocytes. The role of protein phosphorylation in the regulation of NCX1 function inExpand
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Effects of essential oils from herbal plants and citrus fruits on DNA polymerase inhibitory, cancer cell growth inhibitory, antiallergic, and antioxidant activities.
In this study, the biological activity of 20 essential oils (EOs) from herbal plants and citrus fruits were investigated in terms of mammalian DNA polymerase (pol) inhibitory activity, cancer cellExpand
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Inhibitory Effects of Water-Soluble Low-Molecular-Weight β-(1,3-1,6) D-Glucan Isolated from Aureobasidium pullulans 1A1 Strain Black Yeast on Mast Cell Degranulation and Passive Cutaneous Anaphylaxis
We investigated the effects of water-soluble low-molecular-weight β-(1,3-1,6) D-glucan isolated from Aureobasidium pullulans 1A1 strain black yeast (LMW-β-glucan) on mast cell-mediated anaphylacticExpand
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Inhibitory effects of geranium essential oil and its major component, citronellol, on degranulation and cytokine production by mast cells
We investigated the effects of geranium essential oil (GEO) on anaphylaxis. GEO can exert antioxidant and anti-inflammatory effects, but its roles in allergic reactions are incompletely understood.Expand
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Inhibitory Effects of Guarana Seed Extract on Passive Cutaneous Anaphylaxis and Mast Cell Degranulation
This study investigated the effects of guarana seed extract (GSE) on an anti-allergic mechanism. GSE orally administered inhibited the anti-dinitrophenol IgE-induced passive cutaneous anaphylaxisExpand
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Protective effects of Ca2+ handling drugs against abnormal Ca2+ homeostasis and cell damage in myopathic skeletal muscle cells.
Deficiency of delta-sarcoglycan (delta-SG), a component of the dystrophin-glycoprotein complex (DGC), causes skeletal muscular dystrophy and cardiomyopathy in BIO14.6 hamsters. Here, we studied theExpand
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Variants in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.
Loss-of-function mutations of flavin-containing monooxygenase 3 (FMO3), the enzyme responsible for trimethylamine N-oxygenation, cause the inherited disorder trimethylaminuria, or fish odor syndrome.Expand
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