Yukiya Hakozaki

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BACKGROUND/AIMS The mannose-binding lectin (MBL) gene was reported to play an important role in determining the clinical outcome of persistent hepatitis B virus (HBV) infection. We investigated serum MBL concentrations and MBL gene mutations to determine whether they were related to the prognosis of patients with fulminant hepatic failure (FHF) caused by(More)
We have attempted to predict the development of fulminant hepatic failure at the stage of severe acute hepatitis before the onset of coma. This prediction is valuable because it may be used to block the development of fulminant hepatic failure with appropriate medical treatment. Methods: To establish a discrimination formula, we retrospectively compared 13(More)
OBJECTIVES The efficacy of three different dose treatments of interferon (IFN) was evaluated in patients with chronic hepatitis C (HCV). METHODS Ninety-one patients with chronic hepatitis C were allocated to receive 3, 6, or 10 U of recombinant IFN-alpha 2b three times weekly for 24 wk. The number of patients was 26, 35, and 30 in the low, middle, and(More)
OBJECTIVES In places of mass gathering, rapid infection screening prior to definite diagnosis is vital during the epidemic season of a novel influenza. In order to assess the possibility of clinical application of a newly developed non-contact infection screening system, we conducted screening for influenza patients. MATERIALS AND METHODS The system is(More)
OBJECTIVES To classify higher-risk influenza patients within 10 s, we developed an infectious disease and fever screening radar system. METHODS The system screens infected patients based on vital signs, i.e., respiration rate measured by a radar, heart rate by a finger-tip photo-reflector, and facial temperature by a thermography. The system segregates(More)
OBJECTIVE Infrared thermography systems have been used for fever screening at many airports since the outbreak of severe acute respiratory syndrome (SARS) in 2003. However, many of these systems are expensive and non-portable. Therefore, we developed a cost-effective and compact (2.9 × 5.8 × 2.0 cm) thermopile array for fever screening of patients with(More)
OBJECTIVES During the long-term follow-up of chronic hepatitis C patients treated with interferon alpha-2b, we have identified some patients who had continuous normalization, or transient elevation of the serum alanine aminotransferase levels within the first 6 months of follow-up and subsequent normalization, but HCV RNA was still found to be positive(More)