Yukinobu Saitoh

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We have studied the recovery of post-tetanic count and train-of-four responses at the great toe and thumb accelerographically after the administration of vecuronium 0.2 mg.kg-1. Sixty adult patients scheduled for anaesthesia with nitrous oxide and isoflurane were studied. The times to the return of the first post-tetanic twitch were comparable at the great(More)
We sought to determine the characteristics of brain perfusion in patients with corticobasal degeneration (CBD) using single photon emission computed tomography (SPECT) and statistical parametric mapping (SPM). Thirteen patients with CBD and 10 age-matched healthy volunteers were examined using brain perfusion SPECT and (99m)Tc-ethyl cysteinate dimer (ECD).(More)
We have studied the relationship between post-tetanic twitch (PTT) and single twitch response after administration of vecuronium 0.2 mg kg-1 in 100 patients during neuroleptanaesthesia (NLA) (droperidol and fentanyl) and during anaesthesia with halothane, isoflurane, enflurane or sevoflurane (1 MAC in nitrous oxide and oxygen). Intervals from PTT1 to single(More)
We have studied detection of fade in response to train-of-four (TOF), double-burst stimulation3,3 (DBS3,3) or DBS3,2, assessed tactilely by the anaesthetist using the index finger of the non-dominant hand and the thumb of the patient, compared with that assessed when the index finger of the dominant hand was used. The probability of detection of any fade in(More)
We have assessed neuromuscular block electromyographically at the gastrocnemius muscle and compared it with that at the abductor digiti minimi muscle in 60 adult patients undergoing cervical spine surgery under general anaesthesia. All patients were in the prone position. After vecuronium 0.2 mg kg-1, times to onset of neuromuscular block at the(More)
We examined post-tetanic count (PTC) and train-of-four (TOF) ratios at the great toe assessed accelographically or mechanically and compared these with post-tetanic count and train-of-four ratios evaluated mechanically at the thumb in 24 patients who were given vecuronium. An acceleration transducer was attached to the right great toe, a force transducer to(More)
The purpose of this study was to compare the pattern of recovery from vecuronium 0.07 mg.kg-1 induced neuromuscular blockade using post-tetanic burst count (PTBC)-(three short tetanic bursts of 0.2 msec duration every 20 msec given every second following a tetanus), and post-tetanic count (PTC)-(0.2 msec single twitch stimuli given every second following a(More)
We investigated the accelographic train-of-four response evaluated at the great toe at varying stimulating currents. Fifteen adult patients undergoing elective general anaesthesia were studied. The mean current at which a supramaximal T1 value could be elicited was > 49 (9) mA [mean (SD)]. Ratios of accelographic T1 values at 50, 40, 30, 20 and 10 mA to(More)
BACKGROUND Using modified double burst stimulation (modified DBS), sufficient level of recovery from neuromuscular blockade (train-of-four (TOF) ratio > 0.7) can properly be diagnosed. Modified DBS may often be applied in awake patients in the postanesthetic care unit. As the stimulating current decreases, the neurostimulation-induced discomfort becomes(More)
We examined the percentage of tactile detection of fade in response to train-of-four (TOF), double burst stimulation3,3 (DBS3,3), or DBS3,2 at the index finger compared with that at the thumb during continuous infusion of vecuronium. One hundred five adult patients were studied. At TOF ratios (T4/T1) of 0.41-0.70, fades in response to TOF were more(More)