Mili, a mammalian member of piwi family gene, is essential for spermatogenesis
- Satomi Kuramochi-Miyagawa, Tohru Kimura, T. Nakano
- BiologyDevelopment
- 15 February 2004
The similarities in the phenotypes of the MILI- and MVH-deficient mice and in the physical binding properties of MILI and MVh indicate a functional association of these proteins in post-transcriptional regulation, and indicate that MILI is essential for the differentiation of spermatocytes.
Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production
- Tohru Kimura, A. Suzuki, T. Nakano
- BiologyDevelopment
- 15 April 2003
Experiments with PTEN-null PGCs in culture revealed that these cells had greater proliferative capacity and enhanced pluripotent embryonic germ (EG) cell colony formation, and PTEN appears to be essential for germ cell differentiation and an important factor in testicular germ cell tumor formation.
Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells
- Masatake Sato, Tohru Kimura, T. Nakano
- BiologyMechanisms of Development
- 1 April 2002
Two mouse piwi-related genes: miwi and mili
- Satomi Kuramochi-Miyagawa, Tohru Kimura, T. Nakano
- BiologyMechanisms of Development
- 1 October 2001
Mouse Germ Cell-Less as an Essential Component for Nuclear Integrity
- Tohru Kimura, C. Ito, T. Nakano
- BiologyMolecular and Cellular Biology
- 15 February 2003
The mgcl-1 gene product appears to be essential for appropriate nuclear-lamina organization, which in turn is essential for normal sperm morphogenesis and chromatin remodeling, considering that the first abnormality during the process of sperMatogenesis was abnormal nuclear envelope structure in spermatocytes.
Serologic Markers in Relation to Parasite Exposure History Help to Estimate Transmission Dynamics of Plasmodium vivax
- F. Yıldız Zeyrek, N. Palacpac, C. Coban
- MedicinePLoS ONE
- 29 November 2011
A sero-immunological study evaluating antibody responses of individuals living in Sanliurfa to four different P. vivax antigens suggests that a prior history of malaria infection and age can be determining factors for the levels and sustainability of naturally acquired antibodies.
Direct molecular mass determination of trehalose monomycolate from 11 species of mycobacteria by MALDI-TOF mass spectrometry.
- Yukiko Fujita, T. Naka, T. Doi, I. Yano
- Biology, ChemistryMicrobiology
- 1 May 2005
Direct estimation of the molecular mass of single molecular species of trehalose 6-monomycolate (TMM), a ubiquitous cell-wall component of mycobacteria, was performed by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry and showed a marked difference in the molecular species composition of TMM among my cobacterial species.
Comparable studies of immunostimulating activities in vitro among Mycobacterium bovis bacillus Calmette-Guérin (BCG) substrains.
- D. Hayashi, T. Takii, K. Onozaki
- BiologyFEMS Immunology & Medical Microbiology
- 1 July 2009
The results suggest that 'early-shared strains' of BCG are more potent immunostimulating agents than 'late- shared strains', which could be attributed partially to methoxymycolate.
Comprehensive analysis of mycolic acid subclass and molecular species composition of Mycobacterium bovis BCG Tokyo 172 cell wall skeleton (SMP-105).
- Y. Uenishi, Yukiko Fujita, N. Kusunose, I. Yano, M. Sunagawa
- Chemistry, BiologyJournal of Microbiological Methods
- 1 February 2008
Differences in serological responses to specific glycopeptidolipid-core and common lipid antigens in patients with pulmonary disease due to Mycobacterium tuberculosis and Mycobacterium avium complex.
- Yukiko Fujita, T. Doi, R. Maekura, Masami Ito, I. Yano
- Biology, MedicineJournal of Medical Microbiology
- 1 February 2006
The combination of multiple-antigen ELISA using mycobacterial lipids, including GPL-core and TMM-M, gives good discrimination between healthy controls and sera from patients with TB or MAC disease, although for accurate diagnosis of TB more specific antigen(s) are needed.
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