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BACKGROUND We aimed to evaluate the feasibility of an oral direct thrombin inhibitor, dabigatran, as a periprocedural anticoagulant for use with ablation of atrial fibrillation (AF). METHODS Consecutive patients scheduled to undergo an AF ablation were randomly assigned to receive dabigatran (n = 45) or warfarin (n = 45) to compare their clinical(More)
OBJECTIVES This study investigated the prevalence and electrocardiographic and electrophysiologic characteristics of aortic root ventricular arrhythmias (VAs). BACKGROUND Idiopathic VAs originating from the ostium of the left ventricle may be ablated at the base of the aortic cusps. METHODS We studied 265 patients with idiopathic VAs with an inferior(More)
BACKGROUND The summit of the left ventricle (LV) is the most superior portion of the epicardial LV bounded by an arc from the left anterior descending coronary artery, superior to the first septal perforating branch to the left circumflex coronary artery. Ventricular arrhythmias (VAs) originating from this region may present challenges for catheter(More)
BACKGROUND AND OBJECTIVES Two new oral anticoagulants, rivaroxaban and dabigatran, with no need for anticoagulation monitoring, are available for patients with atrial fibrillation (AF). We aimed to compare their anticoagulant effects and safety when used during the AF ablation periprocedural period. METHODS Patients undergoing AF ablation were randomly(More)
BACKGROUND The left atrial appendage (LAA) is one of the major sources of focal atrial tachycardias (ATs). OBJECTIVE The purpose of this study was to investigate the detailed electrophysiologic characteristics and catheter ablation of focal ATs originating from the LAA. METHODS The study population consisted of 47 consecutive patients with 50 focal ATs(More)
BACKGROUND Medical therapy of atrial fibrillation (AF) can be challenging in patients with Brugada electrocardiograms (ECGs). The purpose of this study was to investigate the efficacy of pulmonary vein (PV) isolation (PVI) in AF patients with Brugada ECGs. METHODS AND RESULTS PVI was performed in 6 consecutive patients exhibiting Brugada ECGs (type I in(More)
BACKGROUND Idiopathic ventricular arrhythmias (VAs) can originate from the left ventricular papillary muscles (PAMs). This study investigated the electrophysiological characteristics of these VAs and their relevance for the results of catheter ablation. METHODS AND RESULTS We studied 19 patients who underwent successful catheter ablation of idiopathic VAs(More)
BACKGROUND A fulminant course can be difficult to predict at the onset of acute myocarditis, so the aim of the present study was to identify the predictive clinical symptoms/signs or laboratory findings. METHODS AND RESULTS Thirty-nine patients with acute lymphocytic myocarditis, excluding 8 who manifested shock at admission, were studied. The fulminant(More)
BACKGROUND Mapping of premature ventricular contractions (PVCs) originating from the right ventricular outflow tract (RVOT) sometimes is not easy because of an unstable incidence and multiple foci of the PVCs. The aim of this study was to evaluate the effectiveness of electroanatomic mapping in catheter ablation of those PVCs. METHODS AND RESULTS One(More)
OBJECTIVES The purpose of this study was to examine the relationship between the origin and breakout site of idiopathic ventricular tachycardia (VT) or premature ventricular contractions (PVCs) originating from the myocardium around the ventricular outflow tract. BACKGROUND The myocardial network around the ventricular outflow tract is not well known. (More)