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  • Yukihiko Shirayama, Andrew Chen, Shin Ichi Nakagawa, David S Russell, Ronald S. Duman
  • Biology, Medicine
  • The Journal of Neuroscience
  • 2002 (First Publication: 15 April 2002)
  • Previous studies demonstrated that antidepressant treatment increases the expression of brain-derived neurotrophic factor (BDNF) in rat hippocampus. The present study was conducted to test theExpand
  • Yukihiko Shirayama, Hisahito Ishida, Masaaki Iwata, Gen-i Hazama, Ryuzou Kawahara, Ronald S. Duman
  • Medicine, Biology
  • Journal of neurochemistry
  • 2004 (First Publication: 1 September 2004)
  • Rats exposed to learned helplessness (LH), an animal model of depression, showed a recovery following an intracerebroventricular injection of nor-binaltorphimine dihydrochloride (norBNI; aExpand
  • Andrew Chen, Yukihiko Shirayama, Kyung-ho Shin, Rachael L. Neve, Ronald S. Duman
  • Psychology, Medicine
  • Biological Psychiatry
  • 2001 (First Publication: 1 May 2001)
  • BACKGROUND Recent studies have demonstrated that chronic antidepressant treatment increases the expression of the cyclic amp (cAMP) response element binding protein (CREB) in rat hippocampus. TheExpand
  • Lin Zhang, Yukihiko Shirayama, Masaomi Iyo, Kenji Hashimoto
  • Psychology, Medicine
  • Neuropsychopharmacology
  • 2007 (First Publication: 1 September 2007)
  • The present study was undertaken to examine whether the second generation antibiotic drug minocycline attenuates behavioral changes (eg, acute hyperlocomotion and prepulse inhibition (PPI) deficits)Expand