Yukie Yoshida

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A type III secretion system (T3SS) is utilized by a large number of gram-negative bacteria to deliver effectors directly into the cytosol of eukaryotic host cells. One essential component of a T3SS is an ATPase that catalyzes the unfolding of proteins, which is followed by the translocation of effectors through an injectisome. Here we demonstrate a(More)
To prevent "life style-related diseases", it is necessary to evaluate not only the factors directly related to sleep but also the relationship between sleep and other life style-related factors (such as smoking, alcohol drinking, food habits, and exercise routines). There have been no extensive studies conducted on these relationships. A survey was(More)
Malnutrition has been widely regarded as a healthcare problem among elderly people. The serum albumin level is usually used to assess nutritional status, with less than 3.5g/dl of serum albumin concentration defined as ''hypoalbuminemia''. Low serum albumin level was related with poor health status among not only institutionalized or hospitalized elderly(More)
For participants of diabetes prevention programs, we consider that it is effective to record vital signs, such as weight and blood pressure, and to receive instruction based on such readings during the follow-up period in order to avoid rebound. Although the Internet is an effective medium for recording data and reporting everyday health status, health(More)
Circulating microRNAs (miRNAs) have been detected in various types of cancer and have been proposed as novel biomarkers for diagnosis and treatment. Until recently, however, no studies had comprehensively examined circulating miRNAs in oral cancer. The current study used an ultra-sensitive genome-wide miRNA array to investigate changes in circulating miRNAs(More)
A 78-year-old woman visited a local clinic because of cough and fever, and was prescribed levofloxacin, carbocisteine, and cold medicine (salicylamide, acetaminophen, anhydrous caffeine, promethazine methylene disalicylate). The following day, erythema appeared on the trunk, and spread. Multiple pustules independent of hair follicles developed on the(More)
Several epidemiologic studies have shown the association between total leukocyte count and the risk of developing myocardial infarction. The purpose of this study was to assess the association between the total leukocyte and neutrophil counts and risk factors of ischemic heart disease in 1,384 Japanese factory workers. Total leukocyte and neutrophil counts(More)
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