Yukie Sakuma

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In female rats anesthetized with urethane, 151 neurons in and around the ventromedial nucleus of the hypothalamus were identified by antidromic activation as having axonal projection to the mesencephalic central gray at the midcollicular level. Identified neurons were most numerous in the rostral part and at the borders of the nucleus. Antidromic spike(More)
Rats were adapted to a feeding period of 5 hours per day and meal-fed a diet containing 10% casein, wheat-gluten, corn-gluten, soya protein, gelatin or whole egg protein as a source of protein. The aggregation of hepatic polyribosomes was highest with whole egg protein as the protein source, followed by casein, soya protein, corn-gluten, wheat-gluten and(More)
Electrical stimulation of the medial amygdala (AMY) elicited antidromic action potentials in neurons in the preoptic area (POA) and the lateral septum (LS) of 36 urethane-anesthetized ovariectomized female rats, which were either treated with estrogen o not treated. The extracellular potentials from the two sites showed similar characteristics, with the(More)
Attempts were made to identify hypothalamic neurosecretory cells which participate in the anterior pituitary control with a special reference to the effects of ovarian hormones. Wave forms of the antidromically activated action potentials in the hypothalamus were investigated in the female rats of Wistar strain. The animals of different endocrinological(More)
Many patients with immunoglobulin M (IgM) monoclonal gammopathy remain asymptomatic and, consequently, untreated; however, few studies have evaluated the clinical course and prognosis of these patients. Using the screening procedures at our hospital, 74 patients with IgM monoclonal gammopathy were selected. We excluded 11 patients in whom the treatment for(More)
For optimizing CD34+ cell collection, appropriately timing peripheral blood stem cell harvest (PBSCH) initiation is crucial. Automatic cell analyzers with the immature myeloid information channel provide hematopoietic progenitor cell (HPC) count, a surrogate marker of CD34+ cells, which can be obtained within a few minutes without requiring monoclonal(More)
Attempts were made to investigate the chemical nature of hypothalamic afferents from the extrahypothalamic structures which participate in the control of hypothalamic neurosecretory cells. Experimental procedures were discribed in the preceding report, except that of the electrical stimulation and the microinontophoresis. Some part of data obtained in this(More)
Magnocellular neurosecretory cells were antidromically identified in the hypothalamic paraventricular nucleus (PVN) of urethane-anesthetized, ovariectomized female rats following electrical stimulation of the neurohypophysis. Seventy-one cells with a tonic pattern of spontaneous discharge were distinguished and used to examine the relationships between the(More)
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