Yuki Hikichi

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This paper presents a microwell array that can convert cell-non-adhesiveness of the culture surface to cell-adhesiveness. This microwell array is used to evaluate cellular differentiation behavior by converting cell culture surface. The alginate thin film is used as a material that inhibits adhesion of cells. First, the coating method of alginate gel was(More)
Creation of cell micropatterns comprising heterogeneous cell populations is an important technique for tissue engineering, medical transplantation, drug discovery, and regenerative medicine. This paper presents a novel gel patterning technique similar to general micromachining for creating cell micropatterns using alginate gel to inhibit cell adhesion. The(More)
In this paper, effects of cell-cell adhesion or cell-substrate adhesion on cellular differentiation are evaluated using a microwell array having convertible culture surface (CCS microwell array). The CCS microwell array is used for limitation of culture area and regulation of the adhesion timing. The CCS microwell array is fabricated by photolithography of(More)
This paper presents a measurement method for Young's modulus of cells using fabricated microdevice. This presented method is based on two processes. A first step is cell compressive experiment using fabricated microdevice. The second step is a theoretical calculation for comparing with the experimental results. Cell compression microdevice was designed for(More)
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