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Monkeys made saccades to one of two peripheral targets based on the brightness of a central stimulus. Task difficulty was manipulated by varying the ratio of stimulus black-and-white pixels. Correct response probability for two monkeys varied directly with difficulty. Deep layer SC neurons exhibited robust presaccadic activity the magnitude of which was(More)
The special areal and laminar distributions of cortical afferent connections from various thalamic nuclei in the monkey (Macaca fuscata) were studied by using the anterograde axonal transport technique of autoradiography. The following findings were obtained. The superficial thalamocortical (T-C) projections, terminating in the (superficial half of)(More)
Topographical projections from the thalamus, subthalamic nucleus (STN) and pedunculopontine tegmental nucleus (PPN) to the striatum were examined in the Japanese monkey (Macaca fuscata) by using the retrograde axonal transport technique of WGA-HRP (wheat germ agglutinin-conjugated horseradish peroxidase). After WGA-HRP injection in the head of the caudate(More)
Japanese monkeys consumed two kinds of food, the novel almonds and the familiar sweet potatoes, simultaneously, and then received a cyclophosphamide injection (20 mg/kg) intravenously. As the food-poison pairing was repeated, they first avoided the novel food completely, and then came to suppress eating the familiar one. During the subsequent extinction(More)
Our findings revealed the nucleus ventralis lateralis pars oralis (VLo) projection to motor area, and the nucleus ventralis anterior pars principalis (VApc) projections to the premotor and supplementary motor areas (SMA). The VLo gave rise to thalamocortical projections terminating in the superficial half of layer I, mainly in the forelimb motor area. The(More)
In Experiment 1, 3 mother-child pairs of Japanese monkeys (Macaca fuscata) were given simultaneous choice tests between raisins and popcorn. The mothers and offspring showed different choice patterns. Cofeeding opportunities were then alternated with individual choice tests. In Experiment 2,2 other pairs were added. Each animal was again offered(More)
The spinofacial projection was revealed using anterograde transport of radioactively labeled protein in the monkey. The projection arises from cells in the lateral part of the spinal dorsal horn (i.e. the lateral part of lamina V of Rexed) at the upper cervical cord, mainly C1 segment, ascends in the medial or ventromedial part of the anterior funiculus(More)
While some decision-making processes often result in the generation of an observable action, for example eye or limb movements, others may prevent actions and occur without an overt behavioral response. To understand how these decisions are made, one must look directly at their neuronal substrates. We trained two monkeys on a go/no-go task which requires a(More)
Monkeys made saccades to one of 2 peripheral targets based upon the brightness of a central stimulus. Task difficulty was manipulated by varying the ratio of stimulus black and white pixels. Correct response probability for 2 monkeys varied directly with difficulty. Deep layer SC neurons exhibited robust presaccadic activity whose magnitude was unaffected(More)