Yuji Shimada

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Background and Objective. H. pylori infection causes a chronic inflammation in the gastric mucosa. However, this local inflammation may result in extra-digestive conditions. Our aim is to investigate the relationship between H. pylori infection and osteoporosis in Japan. Methods. This cross-sectional study was conducted among outpatients at the Juntendo(More)
In recent years, many accounting scandals have been reported in companies not only in the United States, but also in Japan. The need for Internal Control is thus growing steadily. In particular, auditing logs are important for Internal Control, although without an audit function, any Internal Control is incomplete. The cost of an information system is(More)
In recent years, many accounting scandals have been reported in companies not only in the United States, but also in Japan. The need for Internal Control is growing steadily. In particular, auditing logs is important for Internal Control. Internal Control lacking audit is incomplete. In addition, logs are included not only defensive implication but also a(More)
BACKGROUND A number of diseases and drugs may influence bone mineral density; however, there are few reports concerning the relationship between lifestyle-related diseases and osteoporosis in Japan as determined by multivariate analysis. The aim of this study was to investigate the risk factors for osteoporosis and whether infection by or eradication of(More)
The activated partial thromboplastin time (APTT) assay is a basic hemostatic assay based on the time it takes for clots to form in plasma samples after the addition of calcium chloride. It is used to screen for various coagulation disorders. Several previous reports have suggested that magnesium (Mg) might contribute to coagulation reactions by binding to(More)
Background. We investigated the prevalence, symptoms, and QOL impact of esophageal (EI), gastric (GI), and duodenal mucosal injury (DI) individually between low-dose aspirin (LDA) users and nonusers to reveal the clinical features of LDA-related mucosal injury. Methods. Data were extracted from the records of subjects who underwent upper gastrointestinal(More)
In recent years, many accounting scandals have been reported in companies not only in the United States, but also in Japan. The need for Internal Control is growing steadily. In particular, auditing logs are important for Internal Control. Any Internal Control without audits is incomplete. Furthermore, logs are necessary not only for defensive implications,(More)
The aim of the present study was to investigate the efficacy of a potassium-competitive acid blocker (PCAB) named vonoprazan (VPZ) for improving symptoms in patients with reflux esophagitis (RE), non-erosive reflux disease (NERD), and functional dyspepsia (FD). A hospital-based, retrospective study of outpatients in our department (Department of(More)
We aimed to clarify the association between a novel serum fibrosis marker, Wisteria floribunda agglutinin-positive Mac-2-binding protein (WFA⁺-M2BP), and hepatocellular carcinoma (HCC) development in 355 patients with chronic hepatitis C who achieved sustained virologic response (SVR) through interferon-based antiviral therapy. Pretreatment serum WFA⁺-M2BP(More)
BACKGROUND Because of a change in lifestyle, especially adoption of westernized eating habits, lifestyle-related diseases have become increasingly prevalent. The aim of this study was to investigate the association of medications for lifestyle-related diseases with reflux esophagitis (RE). METHODS We conducted a hospital-based, cross-sectional(More)