Yuji Miyazaki

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N. Takegawa,1 Y. Miyazaki,1 Y. Kondo,1 Y. Komazaki,1 T. Miyakawa,1 J. L. Jimenez,2 J. T. Jayne,3 D. R. Worsnop,3 J. D. Allan,4 and R. J. Weber5 1Research Center for Advanced Science and Technology, University of Tokyo, Tokyo, Japan 2Department of Chemistry and CIRES, University of Colorado, Boulder, Colorado, USA 3The Center for Aerosol and Cloud Chemistry,(More)
Self-regulating systems often use robust oscillatory circuits. One such system controls the chemotactic signaling mechanism of Dictyostelium, where pulses of adenosine 3',5'-monophosphate (cAMP) are generated with a periodicity of 7 minutes. We have observed spontaneous oscillations in activation of the mitogen-activated protein (MAP) kinase ERK2 that occur(More)
To isolate novel auxin-responsive mutants in Arabidopsis (Arabidopsis thaliana), we screened mutants for root growth resistance to a putative antiauxin, p-chlorophenoxyisobutyric acid (PCIB), which inhibits auxin action by interfering the upstream auxin-signaling events. Eleven PCIB-resistant mutants were obtained. Genetic mapping indicates that the(More)
LOV KELCH PROTEIN2 (LKP2), ZEITLUPE (ZTL)/LOV KELCH PROTEIN1 (LKP1) and FLAVIN-BINDING KELCH REPEAT F-BOX1 (FKF1) constitute a family of Arabidopsis F-box proteins that regulate the circadian clock. Over-expression of LKP2 or ZTL causes arrhythmicity of multiple clock outputs under constant light and in constant darkness. Here, we show the significance of(More)
OBJECTIVE To investigate whether and how the endoplasmic reticulum (ER) stress-induced, CCAAT/enhancer-binding protein-homologous protein (CHOP)-mediated pathway regulates myocardial ischemia/reperfusion injury. METHODS AND RESULTS Wild-type and chop-deficient mice underwent 50 minutes of left coronary artery occlusion followed by reperfusion. Expression(More)
Heat capacity measurements were made on aqueous solutions of a triple-helical polysaccharide schizophyllan by precision adiabatic calorimetry over a wide range of concentrations 30.45-90.93 wt % at temperatures between 5 and 315 K. The heat capacity curves obtained were divided into four groups depending on the weight fraction of schizophyllan w regions(More)
[1] Submicron organic aerosol was measured simultaneously with an Aerodyne aerosol mass spectrometer (AMS) and a particle-into-liquid sampler (PILS) capable of measuring water-soluble organic carbon (WSOC) during the winter and summer of 2004 in Tokyo. Both techniques are being used to investigate the formation of secondary organic aerosol (SOA), and the(More)
The spin crossover phenomenon of the recently described spin crossover complex [FeII(DAPP)(abpt)](ClO4)2 [DAPP = bis(3-aminopropyl)(2-pyridylmethyl)amine, abpt = 4-amino-3,5-bis(pyridin-2-yl)-1,2,4-triazole] accompanying an order-disorder phase transition of the ligand was investigated by adiabatic heat capacity calorimetry, far-IR, IR, and Raman(More)
INTRODUCTION Carriers of reduced-function CYP2C19 allele on antiplatelet therapy show diminished platelet inhibition and higher rate of clinical risk. The purpose of this study was to determine cut-off levels of VerifyNow P2Y12 system associated with effective inhibition of on-clopidogrel platelet aggregation to predict carriers of CYP2C19 reduced-function(More)
Endothelial dysfunction precedes the development of clinical atherosclerosis. A decrease in endothelium-derived nitric oxide activity shows impaired vasodilator function and causes arterial intimal hyperplasia or thickening. Others and we have reported the close relation of endothelial function in brachial artery and coronary artery. To compare the(More)