Yuichi Okutani

Learn More
Genetic risk factors for ticlopidine-induced hepatotoxicity were determined in 22 Japanese patients with ticlopidine-induced hepatotoxicity and 85 Japanese patients who tolerated ticlopidine therapy without experiencing adverse reactions. There was a significant correlation between ticlopidine-induced hepatotoxicity and five human leukocyte antigen (HLA)(More)
This is the first report of the successful treatment of advanced biliary tract cancer with gemcitabine single-agent chemotherapy in combination with Juzen-taiho-to (JTT), a Japanese traditional herbal medicine. An 84-year-old woman was referred to our hospital with general fatigue and appetite loss; she was diagnosed with advanced biliary tract cancer and(More)
BACKGROUND In Asians, the risk of irinotecan-induced severe toxicities is related in part to UGT1A1*6 (UGT, UDP glucuronosyltransferase) and UGT1A1*28, variant alleles that reduce the elimination of SN-38, the active metabolite of irinotecan. We prospectively studied the relation between the UGT1A1 genotype and the safety of irinotecan-based regimens in(More)
BACKGROUND We report a successful treatment by plasma exchange(PE) in the case of Miller Fisher syndrome. CASE A 71-year-old woman rapidly developed diplopia and unsteady gait, and was admitted to Minami-matsuyama Hospital on day 3 of her illness. Ophthalmological and neurological examination on admission revealed bilateral complete external(More)
For the application of the glycemic index (GI) to the therapy of diabetes mellitus (DM) in the elderly, effects of aging and foods were studied in 3 groups of subjects, conducting 3 oral tests of equal calories, namely, glucose, white bread (high-GI meal) and kidney beans (low-GI meal). Group I: healthy adults (N = 7), Group II: elderly non-DM (N = 7),(More)
  • 1