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Pathogenesis of Hepatitis C Virus Infection in Tupaia belangeri
ABSTRACT The lack of a small-animal model has hampered the analysis of hepatitis C virus (HCV) pathogenesis. The tupaia (Tupaia belangeri), a tree shrew, has shown susceptibility to HCV infection andExpand
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Self-Enhancement of Hepatitis C Virus Replication by Promotion of Specific Sphingolipid Biosynthesis
Lipids are key components in the viral life cycle that affect host-pathogen interactions. In this study, we investigated the effect of HCV infection on sphingolipid metabolism, especially onExpand
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  • Open Access
Sphingomyelin Activates Hepatitis C Virus RNA Polymerase in a Genotype-Specific Manner
ABSTRACT Hepatitis C virus (HCV) replication and infection depend on the lipid components of the cell, and replication is inhibited by inhibitors of sphingomyelin biosynthesis. We found thatExpand
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  • Open Access
Cationic-cellulose nanofibers: preparation and dyeability with anionic reactive dyes for apparel application.
Continuous effort in research and development of nanofibers for apparel usage has been focused within their functional properties only. We investigated esthetic properties by producing coloredExpand
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An orally available, small-molecule interferon inhibits viral replication
Most acute hepatitis C virus (HCV) infections become chronic and some progress to liver cirrhosis or hepatocellular carcinoma. Standard therapy involves an interferon (IFN)-α-based regimen, andExpand
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Targeted Induction of Interferon-λ in Humanized Chimeric Mouse Liver Abrogates Hepatotropic Virus Infection
Background & Aims The interferon (IFN) system plays a critical role in innate antiviral response. We presume that targeted induction of IFN in human liver shows robust antiviral effects on hepatitisExpand
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  • Open Access
Augmentation of DHCR24 expression by hepatitis C virus infection facilitates viral replication in hepatocytes.
BACKGROUND & AIMS We characterized the role of 24-dehydrocholesterol reductase (DHCR24) in hepatitis C virus infection (HCV). DHCR24 is a cholesterol biosynthetic enzyme and cholesterol is a majorExpand
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Oxygen permeability and the state of water in Nafion® membranes with alkali metal and amino sugar counterions
Abstract The mobility of hydration water and the dissolved oxygen permeability through different cation forms of the Nafion ® membranes were determined. Two alkali metals (Na and K) and two aminoExpand
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Relationship between the dye/additive interaction and inkjet ink droplet formation
Abstract To design adequate ink composition for textile printing, the relationship between the dye/additive interaction and ink performance is investigated. In the present study, the three acid dyesExpand
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Dye aggregation and interaction of dyes with a water‐soluble polymer in ink‐jet ink for textiles
Detailed understanding of the interaction between dyes and additives and the aggregation behaviour of the dye molecules in aqueous solutions is required to develop ink-jet ink for textiles. In theExpand
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