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Transcription and Translation Products of the Cytolysin Gene psm-mec on the Mobile Genetic Element SCCmec Regulate Staphylococcus aureus Virulence
The F region downstream of the mecI gene in the SCCmec element in hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) contains two bidirectionally overlapping open readingExpand
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Ice-binding site of snow mold fungus antifreeze protein deviates from structural regularity and high conservation
Antifreeze proteins (AFPs) are found in organisms ranging from fish to bacteria, where they serve different functions to facilitate survival of their host. AFPs that protect freeze-intolerant fishExpand
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Hyperactive antifreeze protein from an Antarctic sea ice bacterium Colwellia sp. has a compound ice‐binding site without repetitive sequences
Antifreeze proteins (AFPs) are structurally diverse macromolecules that bind to ice crystals and inhibit their growth to protect the organism from injuries caused by freezing. An AFP identified fromExpand
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Cold adaptation of fungi obtained from soil and lake sediment in the Skarvsnes ice-free area, Antarctica.
A total of 71 isolates were collected from lake sediment and soil surrounding lakes in the Skarvsnes area, Antarctica. Based on ITS region sequence similarity, these isolates were classified to 10Expand
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Time-Dependent Interaction between Differentiated Embryo Chondrocyte-2 and CCAAT/Enhancer-Binding Protein α Underlies the Circadian Expression of CYP2D6 in Serum-Shocked HepG2 Cells
Differentiated embryo chondrocyte-2 (DEC2), also known as bHLHE41 or Sharp1, is a pleiotropic transcription repressor that controls the expression of genes involved in cellular differentiation,Expand
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Silkworm Apolipophorin Protein Inhibits Hemolysin Gene Expression of Staphylococcus aureus via Binding to Cell Surface Lipoteichoic Acids*
Background: Silkworm ApoLp protein binds S. aureus cell surfaces and inhibits hemolysin gene expression. Results: ApoLp protein binds LTA. The ApoLp inhibitory effect was attenuated in an LTAExpand
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Smart Contracts for Machine-to-Machine Communication: Possibilities and Limitations
We study the possibilities and limitations of using smart contracts for machine-to-machine communication by designing, implementing, and evaluating AGasP, an application for automated gasoline purchases. Expand
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Silkworm Apolipophorin Protein Inhibits Staphylococcus aureus Virulence*
Silkworm hemolymph inhibits hemolysin production by Staphylococcus aureus. We purified a factor in the silkworm hemolymph responsible for this inhibitory activity. The final fraction with theExpand
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Antifreeze protein activity in Arctic cryoconite bacteria.
Fourteen Arctic bacterial strains belonging to five genera, Cryobacterium, Leifsonia, Polaromonas, Pseudomonas, and Subtercola isolated from sediments found in cryoconite holes of Arctic glaciers,Expand
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Hydrophobic ice-binding sites confer hyperactivity of an antifreeze protein from a snow mold fungus.
Snow mold fungus, Typhula ishikariensis, secretes seven antifreeze protein isoforms (denoted TisAFPs) that assist in the survival of the mold under snow cover. Here, the X-ray crystal structure of aExpand
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