Yufeng Xu

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In this paper, we present some new existence and uniqueness results for nonlinear fractional differential equations with a kind of general irregular boundary condition in Banach space by using a fixed-point theorem and contraction mapping principle. Moreover, the boundary condition is extended, therefore, some conclusions from other references are special(More)
m.3243A>G mutation in mitochondrial DNA is the most common pathogenic point mutation, causing a variety of phenotypes. To further elucidate its clinical characteristics, we recruited 47 Chinese families carrying m.3243A>G mutation and analyzed their symptoms, disease history, inheritance, and mitochondria-related complications. In the probands, lactic(More)
The numerical solution of a variable-order fractional financial system is calculated by using the Adams-Bashforth-Moulton method. The derivative is defined in the Caputo variable-order fractional sense. Numerical examples show that the Adams-Bashforth-Moulton method can be applied to solve such variable-order fractional differential equations simply and(More)
The genotype-phenotype relationship in diseases with mtDNA point mutations is still elusive. The maintenance of wild-type mtDNA copy number is essential to the normal mitochondrial oxidative function. This study examined the relationship between mtDNA copy number in blood and urine and disease severity of the patients harboring A3243G mutation. We recruited(More)
Large deletions in mitochondrial DNA (mtDNA) may be involved in the pathogenesis of mitochondrial disease. In this study, we investigated the relationship between a 4,977-bp deletion in the mitochondrial genome (ΔmtDNA(4977)) and the severity of clinical symptoms in patients with mitochondrial disease lacking known point mutations. A total of 160 patients(More)
Rapid and adequate vascularization is vital to the long-term success of porous orbital enucleation implants. In this study, porous hydroxyapatite (HA) scaffolds coated with vascular endothelial growth factor (VEGF)-functionalized collagen (COL)/heparin (HEP) multilayers (porosity 75%, pore size 316.8 ± 77.1 μm, VEGF dose 3.39 ng/mm(3)) were fabricated to(More)
OBJECTIVE To compare multi-detector computed tomography (MDCT) with cardiac catheterization and transthoracic echocardiography (TTE) in comprehensive evaluation of the global cardiovascular anatomy in patients with pulmonary atresia with ventricular septal defect (PA-VSD). METHODS The clinical and imaging data of 116 patients with PA-VSD confirmed by(More)