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The characteristic brain pathology and motor and nonmotor symptoms of Parkinson's disease (PD) are well established. However, the details regarding the causes of the disease and its course are much less clear. Animal models have significantly enriched our current understanding of the progression of this disease. Among various neurotoxin-based models of PD,(More)
This paper proposes an efficient constraint-based optimization model for the design of 3G mobile networks, such as universal mobile telecommunications system (UMTS). The model concerns about finding a set of sites for locating radio network controllers (RNCs) from a set of pre-defined candidate sites, and at the same time optimally assigning node Bs to the(More)
There are many aspects that have to be considered during planning phase of 3G networks. Some of the most important factors are: quality of service (QoS), cost of implementation and provisioning, traffic coverage ratio, and resource utilization. This paper analyzes planning aspects of 3G mobile radio network deployment and proposes optimization models which(More)
We developed an integrative spiking neuron framework to study motor learning and control across multiple levels of biological organisations from synaptic learning rules via neural populations and muscles to an arm’s movements. Our framework is designed to simulate reward-based motor learning processes by using identified cellular learning mechanisms(More)
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