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D-cyclins are universally dysregulated in multiple myeloma and frequently overexpressed in leukemia. To better understand the role and impact of dysregulated D-cyclins in hematologic malignancies, we conducted a high-throughput screen for inhibitors of cyclin D2 transactivation and identified 8-ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene (S14161), which(More)
With the rapid development of network technology, current workflow system has become service-based. But the services in current service-based workflow system are either totally public or hidden. The paper presents a service-oriented workflow model which is composed of two types of workflow service: private and public. The private service is the full(More)
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