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Diffuse optical tomography (DOT) has been used by several groups to assess cerebral hemodynamics of cerebral ischemia in humans and animals. In this study, we combined DOT with an indocyanine green (ICG)-tracking method to achieve interleaved images of cerebral hemodynamics and blood flow index (BFI) using two middle cerebral artery occlusion (MCAO) rat(More)
A numerical method for an inverse problem for an elliptic equation with the running source at multiple positions is presented. The so-called " approximate global convergence " property of this method is proved for the discrete case. The performance of the algorithm is verified on experimental data for Diffusion Optical Tomography. Direct applications are in(More)
In this paper, a novel reconstruction method is presented for Near Infrared (NIR) 2-D imaging to recover optical absorption coefficients from laboratory phantom data. The main body of this work validates a new generation of highly efficient reconstruction algorithms called " Globally Convergent Method " (GCM) based upon actual measurements taken from(More)
AIMS/INTRODUCTION Dipeptidyl peptidase-4 (DPP-4) inhibitors are a new class of oral antidiabetic agents, and have been increasingly and widely used in the treatment of diabetes mellitus (DM). However, information of DPP-4 inhibitors in type 2 DM patients with severe renal impairment (RI) is limited. Our study aimed to assess the efficacy and safety of DPP-4(More)
BACKGROUND To date, over 150 genetically modified (GM) crops are widely cultivated. To comply with regulations developed for genetically modified organisms (GMOs), including labeling policies, many detection methods for GMO identification and quantification have been developed. RESULTS To detect the entrance and exit of unauthorized GM crop events in(More)
Endothelial cell (EC) injury or dysfunction is believed to be mediated at least in part by lipopolysaccharide (LPS). Recent studies have shown that LPS induces apoptosis in different types of endothelium, including HUVEC. Previously we used EOLA1 (endothelial-overexpressed LPS-associated factor 1) cDNA as a bait and performed a yeast two-hybrid screening of(More)
A numerical method for an inverse problem for an elliptic equation with the running source at multiple positions is presented. This algorithm does not rely on a good first guess for the solution. The so-called "approximate global convergence" property of this method is shown here. The performance of the algorithm is verified on real data for Diffusion(More)
Metallothioneins (MTs) are a family of low molecular-weight and cysteine-rich metalloproteins that regulate metal metabolism and protect cells from oxygen free radicals. Recent studies suggested that MTs have some anti-inflammatory effects. However, the role of MTs in post-burn inflammation remains unclear. This study is designed to investigate the role of(More)
BACKGROUND Clinicians may use several biochemical markers of bone turnover to assess or guide the care of patients with chronic kidney disease (CKD). The aims of this study are to describe changes and correlations of markers of bone remodeling in patients with different stages of CKD. METHODS A total of 317 Chinese patients with advanced CKD (stage 3-5)(More)