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JNK inhibitor SP600125 protects against lipopolysaccharide-induced acute lung injury via upregulation of claudin-4
Although in vitro studies have previously demonstrated that mitogen-activated protein kinases are important for the activation of transcription factors and the regulation of proinflammatoryExpand
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Protective effect of bone marrow derived mesenchymal stem cells in lipopolysaccharide-induced acute lung injury mediated by claudin-4 in a rat model.
Our study aims to investigate the effects of bone marrow derived mesenchymal stem cells (BM-MSCs) in lipopolysaccharide (LPS)-induced acute lung injury (ALI) as well as the underlying mechanism. InExpand
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[Overexpression of LaeA enhances mevastatin production and reduces sporulation of Penicillium citrinum].
OBJECTIVE To study the regulation of laeA overexpression on mevastatin production and sporulation in Penicillium citrinum. METHODS We cloned the laeA gene from Penicillium citrinum and constructedExpand
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Hsp 90 protects LPS induced pancreatic inflammation of AR 42 J cells by inhibition of p 38 MAPK / NF-κB pathways
Aims: The purpose of this study was to evaluate the role of Hsp90 in the AR42J treated with LPS through over-expression and knock-out Hsp90. This study has further expounded the mechanism that Hsp90Expand