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Dysregulation of apoptosis, specifically overexpression of soluble Fas (sFas), has been proposed to play a role in the development of ovarian cancer. The main objective of the present study was to evaluate serum sFas as a potential biomarker of ovarian cancer risk. The association between serum sFas levels and the risk of ovarian cancer was examined in a(More)
Syncytiotrophoblasts (SCTs) are directly bathed by maternal blood and, as such, are in direct contact with proinflammatory stimuli present in the maternal circulation. The extent and nature of cytokine responses induced in SCTs play a central role in the maintenance of pregnancy. Thrombin is a critical mediator of tissue factor-initiated blood coagulation.(More)
OBJECTIVE Amniochorion matrix metalloproteinase (MMP)-9 levels increase during labor, reaching a maximum in patients with preterm premature rupture of membranes (PPROM). Bleeding is a major risk factor for PPROM. Since such hemorrhage into the tissue factor-enriched decidua induces intense thrombin formation, we determined whether thrombin stimulates MMP(More)
Extracellular matrix (ECM) proteins synthesized by human placental mesenchymal cells (PMCs) provide structural support for the villus. Aberrant expression of ECM proteins by PMCs has been associated with intrauterine growth restriction (IUGR). To provide insight into the mechanisms of ECM protein regulation in the stroma of the placental villus, in the(More)
The human placenta is a glucocorticoid (GC)-responsive organ consisting of multiple cell types including smooth muscle cells, fibroblasts, and trophoblast that demonstrate changes in gene expression after hormone treatment. However, little is known about the relative expression or activity of the GC receptor (GR) among the various placental cell types.(More)
PROBLEM The placental syncytium is a differentiated cell type on the surface of the villus that has the potential to release cytokines directly to maternal blood. Responsiveness of this cell type to inflammatory compounds remains largely unelucidated. METHOD OF STUDY Response to a pro-inflammatory (lipopolysaccharide, LPS) and an anti-inflammatory(More)
In this paper, a series of organoclays were prepared from montmorillonites with different CEC and surfactants with different alkyl chain numbers and chain length. Then, FTIR spectroscopy using ATR, DRIFT and KBr pressed disk techniques was used to characterize the local environments of surfactant and host clays in various surfactants modified(More)
The narrow bandwidth of a microstrip antenna is one of the important antennas wide usage In this paper, the design method coupling feed a bandwidth of 10GHz narrowband-ARMSA linearly polarized antenna. When the center frequency of 4.3GHz, the antenna design software simulation and actual test. The simulation results and the actual results are compared to(More)
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