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The stability of the Wnt pathway transcription factor beta-catenin is tightly regulated by the multi-subunit destruction complex. Deregulated Wnt pathway activity has been implicated in many cancers, making this pathway an attractive target for anticancer therapies. However, the development of targeted Wnt pathway inhibitors has been hampered by the limited(More)
Shift-reduce dependency parsers give comparable accuracies to their chart-based counterparts, yet the best shift-reduce constituent parsers still lag behind the state-of-the-art. One important reason is the existence of unary nodes in phrase structure trees, which leads to different numbers of shift-reduce actions between different outputs for the same(More)
Cytoplasmic (or non-muscle) myosin II isoforms are widely expressed molecular motors playing essential cellular roles in cytokinesis and cortical tension maintenance. Two of the three human non-muscle myosin II isoforms (IIA and IIB) have been investigated at the protein level. Transient kinetics of non-muscle myosin IIB showed that this motor has a very(More)
Target-dependent sentiment analysis on Twitter has attracted increasing research attention. Most previous work relies on syntax, such as automatic parse trees, which are subject to noise for informal text such as tweets. In this paper, we show that competitive results can be achieved without the use of syntax , by extracting a rich set of automatic(More)
It has been shown that news events influence the trends of stock price movements. However, previous work on news-driven stock market prediction rely on shallow features (such as bags-of-words, named entities and noun phrases), which do not capture structured entity-relation information , and hence cannot represent complete and exact events. Recent advances(More)
L1 elements are the only active autonomous retrotransposons in the human genome. The nonautonomous Alu elements, as well as processed pseudogenes, are retrotransposed by the L1 retrotransposition proteins working in trans. Here, we describe another repetitive sequence in the human genome, the SVA element. Our analysis reveals that SVA elements are currently(More)