Yue Gu

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Transforming growth factor-beta (TGF-β) type II receptor (TβRII) levels are extremely low in the brain tissue of patients with Alzheimer's disease. This receptor inhibits TGF-β1/SMAD signaling and thereby aggravates amyolid-beta deposition and neuronal injury. Dab2, a specific adapter protein, protects TβRII from degradation and ensures the effective(More)
This paper proposes an approach based on ANN-QPSO (artificial neural network based on quantum-behaved particle swarm optimization) to evaluate integrated business efficiency of enterprise. It uses QPSO to train the neural network to overcome local-best solution in training process. We use a test example with 35 listed enterprises to show the feasibility and(More)
BACKGROUND This study is to report characteristics of people killed in road traffic crashes and to describe major patterns of traffic crashes in China. METHODS Descriptive and inferential statistical analyses were conducted. Road traffic death national data, population denominator data and motor vehicles data of 2009 were obtained from the Bureau of(More)
Celastrol is a triterpenoid compound extracted from the Chinese herb Tripterygium wilfordii Hook F. Previous research has revealed its anti-oxidant, anti-inflammatory, anti-cancer and immunosuppressive properties. Here, we investigated whether celastrol inhibits oxidized low-density lipoprotein (oxLDL) induced oxidative stress in RAW 264.7 cells. In(More)
Lung carcinoma is a deadly malignant disease with poor prognosis and increasing incidence in recent years. However, the molecular mechanism underlying the initiation and progression of lung cancer is still not completely elucidated. Recently, myocyte enhancer factor 2D (MEF2D) has been reported to promote the growth of liver cancer, but its implication in(More)
According to the characteristics of Chinese language, this paper proposes a statistical parsing method based on Maximal Noun Phrase(MNP) per-processing. MNP parsing is preferable to be separated from parsing of the full sentence. Firstly, MNP in a sentence are identified; next, MNP can be represented by the head of MNP, and then the sentence is parsed with(More)
HIFU has been demonstrated to enhance anti-tumor immunity, however, the mechanism of which has not been well elucidated. Emerging evidence indicates that miRNAs play important roles in immune response. In this study, we used the B16F10 melanoma allograft mouse model to investigate the role of miRNAs in HIFU-enhanced anti-tumor immunity. We found that HIFU(More)
Micro-grid plays an important role in the development of Smart Grid. This paper analyzing the existing control method proposed a hybrid operation control method for micro-grid. It realize this control method via multi-Agent technology; Multi-Agent technology represents a multi-intelligent collection with prosperities of logical analysis, independent(More)
We propose a bidirectional reflective semiconductor optical amplifier (RSOA) based wavelength-division-multiplexing passive optical network (WDM-PON) utilizing a differential phase shift keying (DPSK) signal for down-link and an on-off keying (OOK) signal re-modulated for up-link with high extinction-ratio in both directions. A 20 km range colorless WDM-PON(More)
The human disease methylation database (DiseaseMeth, http://bioinfo.hrbmu.edu.cn/diseasemeth/) is an interactive database that aims to present the most complete collection and annotation of aberrant DNA methylation in human diseases, especially various cancers. Recently, the high-throughput microarray and sequencing technologies have promoted the production(More)