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Structural insight into the type-II mitochondrial NADH dehydrogenases
The crystal structures of Ndi1 in its substrate-free, NADH-, ubiquin one- and NADH–ubiquinone-bound states are solved and it is proposed that UQI interacts with FAD to act as an intermediate for electron transfer, and that NADH transfers electrons through this FAD–UQI complex to UQII.
Enhanced extracellular production of L-asparaginase from Bacillus subtilis 168 by B. subtilis WB600 through a combined strategy
To the best of the knowledge, this study obtained the highest yield of ASN in a food-grade host ever reported, which may benefit the industrial production and application of AsN.
Arabidopsis thaliana PRP40s are RNA polymerase II C-terminal domain-associating proteins.
Structural insights into the coordination of plastid division by the ARC6–PDV2 complex
The crystal structure of the intermembrane space region of the ARC6–PDV2 complex is solved and reveals that PDV2-induced dimerization of ARC6 plays a critical role in chloroplast division and provides insights into the coordination mechanism of the internal and external plastid division machineries.
Structure and Function of the Photosystem Supercomplexes
Recent advances in single-particle cryo-electron microscopy, X-ray free electron laser, and other techniques have revealed unprecedented structural and catalytic details concerning the two photosystem supercomplexes, with an emphasis on PSII-LHCII.
Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance
- Xiaozhe Zhang, Jing-jing Wang, Maojun Yang
- BiologyProceedings of the National Academy of Sciences
- 16 October 2012
This study defines the role of the β-barrel in the ion selection of an anion-selective MscS channel and provides a structural basis for understanding the ion selectivity of MSCS channels.
Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB
This study solved the crystal structures of apo-ClfB and its complexes with fibrinogen α (Fg α) and cytokeratin 10 (CK10) peptides and revealed a conserved glycine-serine-rich ClfB binding motif (GSSGXGXXG) within the ligands, which was also found in other human proteins such as Engrailed protein, TCF20 and Dermokine proteins.
Mitochondrial ClpP serine protease-biological function and emerging target for cancer therapy
The structure and function of mitochondrial ClpXP are reviewed as well as strategies to target this enzyme complex as a novel therapeutic approach for malignancy are reviewed.
Arabidopsis SCP1-like small phosphatases differentially dephosphorylate RNA polymerase II C-terminal domain.
AtCPL5, a novel Ser-2-specific RNA polymerase II C-terminal domain phosphatase, positively regulates ABA and drought responses in Arabidopsis.
- Yong-Mei Jin, Jinwook Jung, Minkyun Kim
- Biology, Environmental ScienceThe New phytologist
- 1 April 2011
It is concluded that AtCPL5 is a unique CPL family protein that positively regulates ABA-mediated development and drought responses in Arabidopsis.