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BACKGROUND Chemoresistance is one of the main obstacles to successful cancer therapy and is frequently associated with Multidrug resistance (MDR). Many different mechanisms have been suggested to explain the development of an MDR phenotype in cancer cells. One of the most studied mechanisms is the overexpression of P-glycoprotein (P-gp), which is a product(More)
Ideal MHD equations arise in many applications such as astrophysical plasmas and space physics, and they consist of a system of nonlinear hyperbolic conservation laws. The exact density ρ and pressure p should be non-negative. Numerically, such positivity property is not always satisfied by approximated solutions. One can encounter this when simulating(More)
  • Badara Cisse, Matthew Cairns, Ernest Faye, Ousmane NDiaye, Babacar Faye, Cecile Cames +10 others
  • 2009
BACKGROUND The long terminal half life of piperaquine makes it suitable for intermittent preventive treatment for malaria but no studies of its use for prevention have been done in Africa. We did a cluster randomized trial to determine whether piperaquine in combination with either dihydroartemisin (DHA) or sulfadoxine-pyrimethamine (SP) is as effective,(More)
BACKGROUND Adequate maternal nutrient intake during pregnancy is important to ensure satisfactory birth outcomes. There are no data available on the usual dietary intake among pregnant women in rural China. The present study describes and evaluates the dietary intake in a cohort of pregnant women living in two counties of rural Shaanxi, western China. (More)
Enterprises are increasingly moving their big data analytics to the cloud with the goal of reducing costs without sacrificing application performance. Cloud service providers offer their tenants a myriad of storage options, which while flexible, makes the choice of storage deployment non trivial. Crafting deployment scenarios to leverage these choices in a(More)
  • Yue Cheng, Arthur Kwok Leung Cheung, Josephine Mun Yee Ko, Yee Peng Phoon, Pui Man Chiu, Paulisally Hau Yi Lo +2 others
  • 2013
A few reports suggested that low levels of Wnt signaling might drive cell reprogramming, but these studies could not establish a clear relationship between Wnt signaling and self-renewal networks. There are ongoing debates as to whether and how the Wnt/β-catenin signaling is involved in the control of pluripotency gene networks. Additionally, whether(More)
BACKGROUND Validity of self-reported height and weight has not been adequately evaluated in diverse adolescent populations. In fact there are no reported validity studies conducted in Asian children and adolescents. This study aims to examine the accuracy of self-reported weight, height, and resultant BMI values in Chinese adolescents, and of the(More)
Cloud object stores are increasingly becoming the de facto storage choice for big data analytics platforms, mainly because they simplify the management of large blocks of data at scale. To ensure cost-effectiveness of the storage service, the object stores use hard disk drives (HDDs). However, the lower performance of HDDs affect tenants who have strict(More)