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Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
Acetylation of proteins on lysine residues is a dynamic posttranslational modification that is known to play a key role in regulating transcription and other DNA-dependent nuclear processes. However,Expand
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Open Access
Dynamic activity of lipid droplets: protein phosphorylation and GTP-mediated protein translocation.
Lipid droplet is a cellular organelle with a neutral lipid core surrounded by a phospholipid monolayer and coated with structural as well as functional proteins. The determination of these proteins,Expand
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Phosphoenolpyruvate Carboxylase in Arabidopsis Leaves Plays a Crucial Role in Carbon and Nitrogen Metabolism1
Phosphoenolpyruvate carboxylase in Arabidopsis leaves balances carbon and nitrogen metabolism. Phosphoenolpyruvate carboxylase (PEPC) is a crucial enzyme that catalyzes an irreversible primaryExpand
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Identification of Lysine Succinylation Substrates and the Succinylation Regulatory Enzyme CobB in Escherichia coli*
Lysine succinylation is a newly identified protein post-translational modification pathway present in both prokaryotic and eukaryotic cells. However, succinylation substrates and regulatory enzyme(s)Expand
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Molecular Characterization of Propionyllysines in Non-histone Proteins *S
Lysine propionylation and butyrylation are protein modifications that were recently identified in histones. The molecular components involved in the two protein modification pathways are unknown,Expand
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Open Access
Pharmacokinetic parameters and tissue distribution of magnetic Fe3O4 nanoparticles in mice
Background This study explored the pharmacokinetic parameters and tissue distribution of magnetic iron oxide nanoparticles (Fe3O4 MNPs) in imprinting control region (ICR) mice. Methods The Fe3O4 MNPsExpand
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Open Access
Mitochondrial Phosphoproteome Revealed by an Improved IMAC Method and MS/MS/MS*S
  • J. Lee, Y. Xu, +4 authors Y. Zhao
  • Chemistry, Medicine
  • Molecular & Cellular Proteomics
  • 1 April 2007
IMAC in combination with mass spectrometry is a promising approach for global analysis of protein phosphorylation. Nevertheless this approach suffers from two shortcomings: inadequate efficiency ofExpand
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Comprehensive profiling of protein lysine acetylation in Escherichia coli.
Protein lysine acetylation plays a key role in regulating chromatin dynamics, gene expression and metabolic pathways in eukaryotes, and, thus, contributes to diverse cellular processes likeExpand
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In vitro and in vivo antioxidant effects of the ethanolic extract of Swertia chirayita.
ETHNOPHARMACOLOGICAL RELEVANCE Swertia chirayita, a medicinal herb endemic to the Tibetan region, is used as a special remedy for liver disorders. The hepatoprotective activity of its plant extractsExpand
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Disordered hepcidin-ferroportin signaling promotes breast cancer growth.
Iron homeostasis is strictly governed in mammals; however, disordered iron metabolism (such as excess iron burden) is recognized as a risk factor for various types of diseases including cancers.Expand
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