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Bioactive constituents from the green alga Caulerpa racemosa.
Natural products possessing protein tyrosine phosphatase 1B (PTP1B) inhibitory activity found in the last decades
This article provides an overview of approximately 300 secondary metabolites with inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), which were isolated from various natural sources
Rare casbane diterpenoids from the Hainan soft coral Sinularia depressa.
A series of nine casbane diterpenes, compounds 5-13, exhibiting either cis or trans ring junctions were isolated from the Hainan soft coral Sinularia depressa and the structures of this group of compounds were established by detailed spectroscopic analysis.
Secondary metabolites from the South China Sea invertebrates: chemistry and biological activity.
The article covers the literature published during the period from the beginning of 1980 to the end of 2005, with 340 citations and 811 compounds from invertebrates from the South China Sea, including sponges, coelenterates, molluscs and echinoderms.
Steroids with aromatic A-rings from the Hainan soft coral Dendronephthya studeri Ridley.
Eight new marine steroids, characterized by either the presence of an aromatic ring or a cross-conjugated dienone system in ring A, were isolated from the Hainan soft coral Dendronephthya studeri
Sesquiterpenes from the Hainan Sponge Dysidea septosa.
Five new sesquiterpenes, named lingshuiolides A and B, lingshuiperoxide (6), isodysetherin (10), and spirolinghuiolide (12), along with several known related analogues, were isolated from the Hainan marine sponge Dysidea septosa and exhibited significant inhibitory activity against human protein tyrosine phosphatase 1B.
A sesquiterpene quinone, dysidine, from the sponge Dysidea villosa, activates the insulin pathway through inhibition of PTPases
Dysidine, found in the Hainan sponge Dysidea villosa in the Chinese South Sea, effectively activated the insulin signaling pathway, greatly promoted glucose uptake in 3T3-L1 cells, and showed strong insulin-sensitizing activities.