Yudai Shirasaki

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Sodium nitroprusside (3-100 nM) and sodium nitrite (0.03-1 mM) caused relaxation of the rat aortic ring segments precontracted by norepinephrine. The relaxation was significantly augmented by removal of endothelium, and this augmentation was greater in the aorta from spontaneously hypertensive rats (SHR) than Wistar Kyoto rats (WKY). The mechanism remains(More)
Blood vessel responses to relaxant drugs have been reported to change with aging and with the development of hypertension. In view of the requirement of endothelial cells for the activity of many relaxant drugs, we examined the role of the endothelium in the relaxation response of vascular tissue. Aortic and mesenteric ring segments from normotensive and(More)
The role of endothelial cells in modulating the vascular smooth muscle tone in aging and hypertension was examined. Results from in vitro pharmacological studies indicate that vasodilations of rat arteries induced by several dilator agents, such as nitrovasodilators, decrease with advancing age and experimental hypertension. These diminished dilator(More)
The mechanism whereby endothelial modulation of drug-induced vascular responses might change during hypertension was examined. Acetylcholine (ACh) (1 microM) induced maximal relaxation of aortic ring segments with intact endothelium from both Wistar-Kyoto, normotensive rats (WKY) and spontaneously hypertensive rats (SHR) at 5 to 6 weeks of age. At 15 to 18(More)
This memo is a digest of the user network interface specification of NTT Communications’ dual stack ADSL access service, which provide a IPv6/IPv4 dual stack services to home users. In order to simplify user setup, these services have a mechanism to configure IPv6 specific parameters automatically. The memo focuses on two basic parameters: the prefix(More)
The effects of adenosine on stimulation-evoked 3H-efflux from perfused mesenteric arteries pretreated with 3H-norepinephrine and on norepinephrine-induced contractile responses of the thoracic aorta before and after mechanical removal of endothelial cells were examined in spontaneously hypertensive rats (SHR) compared with Wistar-Kyoto rats (WKY). Adenosine(More)
Genetic Algorithm (GA) is known as method to solve Traveling Salesman Problem (TSP). However, GA needs amount of time for finding approximate solution. Thus, this study proposes Genetic Algorithm with Virus Infection (GAVI). GAVI algorithm is using Virus Theory of Evolution (VTE) to be based on Genetic Algorithm (GA). GA can evolve by natural selection,(More)
In this study, we propose an optimization method by the cooperative mechanism of ant and aphid as a new Ant Colony Optimization (ACO). This algorithm is named Ant Colony Optimization with Cooperative Aphid (ACOCA). In ACOCA algorithm, the aphid searches neighborhood solutions. This solution information is treated as a honey obtained from the aphid and the(More)
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