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Budralazine was evaluated for its protective effect on the onset of cerebrovascular lesions in SHR given 1.5% NaCl as drinking water. The salt-loading for 67 days rapidly accelerated the development of hypertension in SHR (from 180 to over 250 mmHg, 40 days after the loading). The acceleration of hypertension was accompanied by an increase in the incidence(More)
In this study, we propose an optimization method by the cooperative mechanism of ant and aphid as a new Ant Colony Optimization (ACO). This algorithm is named Ant Colony Optimization with Cooperative Aphid (ACOCA). In ACOCA algorithm, the aphid searches neighborhood solutions. This solution information is treated as a honey obtained from the aphid and the(More)
Genetic Algorithm (GA) is known as method to solve Trav-eling Salesman Problem (TSP). However, GA needs amount of time for finding approximate solution. Thus, this study proposes Genetic Algorithm with Virus Infection (GAVI). GAVI algorithm is using Virus Theory of Evolution (VTE) to be based on Genetic Algorithm (GA). GA can evolve by natural selection,(More)
Budralazine was evaluated for its effects on glucose and lipid metabolism in diabetic SHR. SHR treated with 10% sucrose solution as drinking water for 3 months exhibited an impaired glucose tolerance with higher serum insulin levels and a reduction of sigma delta IRI/sigma delta BS. This model was, therefore, considered to resemble hypertensive patients(More)
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