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The new 6q27 tumor suppressor DACT2, frequently silenced by CpG methylation, sensitizes nasopharyngeal cancer cells to paclitaxel and 5-FU toxicity via β-catenin/Cdc25c signaling and G2/M arrest
BackgroundNasopharyngeal carcinoma (NPC) is prevalent in South China, including Hong Kong and Southeast Asia, constantly associated with Epstein-Barr virus (EBV) infection. Epigenetic etiologyExpand
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TrkB promotes laryngeal cancer metastasis via activation PI3K/AKT pathway
Objectives The aim of our study was to investigate the role of TrkB pathway in tumor occurrence and development for in order to provide theoretical basis to laryngeal cancer therapy. Materials andExpand
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Differential Expression and Release of Activin A and Follistatin in Chronic Rhinosinusitis with and without Nasal Polyps
Background Chronic rhinosinusitis with (CRSwNP) and without nasal polyps (CRSsNP) should be regarded as distinct clinical entities based on differential inflammatory mediator and remodeling profiles.Expand
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Knockdown of NFBD1/MDC1 enhances chemosensitivity to cisplatin or 5-fluorouracil in nasopharyngeal carcinoma CNE1 cells
Abstract Nasopharyngeal carcinoma (NPC) is a rare but highly invasive cancer that is prevalent among people of southern Chinese ancestry in southern China and Southeast Asia. Radiotherapy andExpand
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Potential role of MG53 in the regulation of transforming‐growth‐factor‐&bgr;1‐induced atrial fibrosis and vulnerability to atrial fibrillation
&NA; Atrial fibrosis plays a critical role in atrial fibrillation (AF) by the transforming growth factor (TGF)‐&bgr;1/Smad pathway. The disordered differentiation, proliferation, migration andExpand
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[Clinical effectiveness and safety of sanchi tong shu capsule in the treatment of aural vertigo: a multi-center randomized controlled clinical trial].
OBJECTIVE To evaluate the clinical effectiveness and safety of Sanchi Tong Shu capsule in the treatment of common aural vertigo. METHOD A multi-center randomized controlled trial was designed toExpand
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Differential Expression of the Aryl Hydrocarbon Receptor and Transforming Growth Factor Beta 1 in Chronic Rhinosinusitis with Nasal Polyps with Allergic Rhinitis
Objective: This study aimed to determine the aryl hydrocarbon receptor (AhR) and transforming growth factor beta 1 (TGF-β1) expression levels in chronic rhinosinusitis (CRS) and their possibleExpand
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[Analysis of EBV-LMP1 gene mutation in plasma of patients with nasopharyngeal carcinoma in Chongqing].
OBJECTIVE To detect and analyze the EBV-LMP1 gene N terminus XhoI-site mutation and C terminus 30 bp deletion in plasma of patients with nasopharyngeal carcinoma (NPC) in Chongqing of China. METHODExpand
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[Chronic rhinosinusitis and tissue remodeling].
  • L. Fang, Yucheng Yang
  • Medicine
  • Lin chuang er bi yan hou tou jing wai ke za zhi…
  • 1 September 2013
Chronic rhinosinusitis is a common health problem of otorhinolaryngology head and neck surgery, and is characterized by persistent inflammation of the nasal and paranasal mucosal linings. In recentExpand
Comparison of curriculum and degree conferment in higher medical education between Germany and China
The higher medical education in China starts late and needs further exploration and improvement. While in Germany, it is elite education with a long history. Compared with China, in curriculumExpand