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  • Lixin Zhang, Yucheng Tang, Hakan Akbulut, Daniel Zelterman, Phyllis-Jean Linton, Albert B. Deisseroth
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 2003 (First Published: 9 December 2003)
  • To develop a method to overcome the anergy that exists in tumor hosts to cancer, we have designed an adenoviral vector for the in vivo activation and tumor antigen loading of dendritic cells. ThisContinue Reading
  • Lixin Zhang, Hakan Akbulut, +5 authors Albert B. Deisseroth
  • Biology, Medicine
  • Molecular therapy : the journal of the American…
  • 2002 (First Published: 1 September 2002)
  • We have previously demonstrated that a truncated form of the L-plastin promoter can confer tumor-specific patterns of expression on replication-incompetent adenoviral vector reporter and therapeuticContinue Reading
  • Hakan Akbulut, Lixin Zhang, Yucheng Tang, Albert B. Deisseroth
  • Biology, Medicine
  • Cancer Gene Therapy
  • 2003 (First Published: 1 May 2003)
  • Prodrug activating transcription unit gene therapy is one of several promising approaches to cancer gene therapy. Combining that approach with conditionally replication-competent viral vectors thatContinue Reading
  • Pingchuan Li, Yanzheng Liu, Jonathan Leader Maynard, Yucheng Tang, Albert B. Deisseroth
  • Biology, Medicine
  • Molecular therapy : the journal of the American…
  • 2010 (First Published: 1 May 2010)
  • To target chemotherapy to tumor vascular endothelial cells (TVECs), we created the AdTie2RprCDFib(knob-RGD+) vector by inserting into an AdEasy adenoviral vector (Ad) backbone: (i) the cytosineContinue Reading
  • Hakan Akbulut, Yucheng Tang, Jonathan Leader Maynard, Lixin Zhang, Giuseppe Pizzorno, Albert B. Deisseroth
  • Biology, Medicine
  • Clinical cancer research : an official journal of…
  • 2004 (First Published: 15 November 2004)
  • PURPOSE 5-fluorouracil (5-FU) has been combined in the past with other drugs for the combination chemotherapy for cancers of the breast, ovary, and colon. These drug regimens were limited by the factContinue Reading