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Treatment-Related Adverse Events of PD-1 and PD-L1 Inhibitors in Clinical Trials: A Systematic Review and Meta-analysis.
Importance Programmed cell death (PD-1) and programmed cell death ligand 1 (PD-L1) inhibitors have been increasingly used in cancer therapy. Understanding the treatment-related adverse events of… Expand
CA-125 Significance in Cirrhosis and Correlation with Disease Severity and Portal Hypertension: A Retrospective Study
- Raja Gr Edula, Sujit Muthukuru, +4 authors N. Pyrsopoulos
- Journal of clinical and translational hepatology
- 2 July 2018
Abstract Background and Aims: To evaluate the prevalence and significance of elevated cancer antigen-125 (CA-125) levels in patients with cirrhosis being treated in a tertiary care liver center and… Expand
Incidence and risk of diarrhea in cancer patients treated with pertuzumab: Evidence from published studies.
e22216 Background: Pertuzumab is a novel HER2 dimerization inhibitor administered in combination with trastuzumab and docetaxel in the treatment of HER2-positive metastatic breast cancer. Diarrhea ...
Synthesis and characterization of Pd@M(x)Cu(1-x) (M = Au, Pd, and Pt) nanocages with porous walls and a yolk-shell structure through galvanic replacement reactions.
This paper describes the synthesis of Pd@M(x)Cu(1-x) (M = Au, Pd, and Pt) nanocages with a yolk-shell structure through galvanic replacement reactions that involve Pd@Cu core-shell nanocubes as… Expand
Inter-rater reliability of the A-S-C-O classification system for ischemic stroke
Atherosclerosis-small vessel disease-cardiac source-other (A-S-C-O) is a new phenotypic system that categorizes stroke according to a combination of etiologic characteristics. The purpose of this… Expand
Performance investigation for a silicon nanowire FET biosensor using numerical simulation
Silcion field-effect transistor (SiNW FET) biosensors have recently been demonstrated experimentally for direct, label free, high sensitive, high selective and real time detection of DNA and proteins… Expand
Simulation of a silicon nanowire FET biosensor for detecting Biotin/Streptavidin binding
In recent years, detection of DNA and proteins at very low concentration using silicon nanowire (SiNW) field-effect transistor (FET) biosensors have been experimentally demonstrated. Among these… Expand
Docetaxel in the treatment of metastatic hormone-sensitive and castration-resistant prostate cancer: A meta-analysis.
e16505Background: Docetaxel is a chemotherapeutic agent indicated for patients (pts) with metastatic castration-resistant prostate cancer (mCRPC). This study aims to evaluate the efficacy and safet...
Boosting the triplet activity of heavy-atom-free difluoroboron dibenzoylmethane via sp3 oxygen-bridged electron donors.
Purely organic phosphors have important applications in imaging, sensing, informatics and illumination. Methoxy-substituted difluoroboron dibenzoylmethane (BF2dbm) complexes exhibit intense… Expand
Distinct impacts of KRAS, NRAS and BRAF mutations on survival of patients with metastatic colorectal cancer.
3513Background: RAS and BRAF mutations are associated with lack of response to anti-EGFR therapy and worse survival in patients with metastatic colorectal cancer (mCRC). NRAS mutations are less fre...