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The mixture cure model is a special type of survival models and it assumes that the studied population is a mixture of susceptible individuals who may experience the event of interest, and cure/non-susceptible individuals who will never experience the event. For such data, standard survival models are usually not appropriate because they do not account for(More)
Epigenetics is the study of chemical reactions, which are orchestrated for the development and maintenance of an organism. Genetic or epigenetic variants (GEVs) encompass different types of genetic measures, such as Deoxyribonucleic acid (DNA) methylation at different CpG sites, expression level of genes, or single nucleotide polymorphisms (SNPs). With the(More)
Breast cancer is the most common non-skin cancer in women and the second most common cause of cancer-related death in U.S. women. It is well known that the breast cancer survival varies by age at diagnosis. For most cancers, the relative survival decreases with age but breast cancer may have the unusual age pattern. In order to reveal the stage risk and age(More)
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