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Iridoids from the roots of Valeriana jatamansi and their neuroprotective effects.
Absolute Configurations and NO Inhibitory Activities of Terpenoids from Curcuma longa.
The discovery of two new compounds in the ongoing search for inhibitory reagents of NO production and survey of the chemical composition of natural vegetable foods resulted in the isolation of 2 new terpenoids and 14 known analogues, and implied that the natural food spice C. longa, containing terpenoid with NO inhibitory activities, may be potentially promotive to human health.
Diterpenes inhibiting NO production from Euphorbia helioscopia.
Neuroprotective bakkenolides from the roots of Valeriana jatamansi.
Bioactive Diterpenoids from the Stems of Euphorbia royleana.
The nitric oxide inhibitory activities of those diterpenoids were examined biologically in lipopolysaccharide-stimulated BV-2 cells, with compounds 1, 2, 5-7, 10, and 12 having IC50 values lower than 40 μM.
Bioactive myrsinol diterpenoids from the roots of Euphorbia prolifera.
The diterpenes showed neuroprotective effects against MPP+-induced neuronal cell death in SH-SY5Y cells, and the structure of 1 was confirmed by X-ray crystallography.
Withanolides from Physalis peruviana showing nitric oxide inhibitory effects and affinities with iNOS.
Sesquiterpene esters from the fruits of Celastrus orbiculatus.
- Yuanqiang Guo, Xian Li, Jing Xu, Ning Li, Dali Meng, J. Wang
- ChemistryChemical & pharmaceutical bulletin
- 1 September 2004
Three new beta-dihydroagarofuran sesquiterpene esters isolated from the fruits of Celastrus orbiculatus THUNB showed moderate activity in inhibiting LPS-induced nitric oxide production in murine macrophage RAW264.
Isolation, Structural Elucidation, and Neuroprotective Effects of Iridoids from Valeriana jatamansi
- Jing Xu, Yushan Li, Yuanqiang Guo, Ping-Xia Guo, T. Yamakuni, Y. Ohizumi
- ChemistryBioscience, biotechnology, and biochemistry
- 23 July 2012
Two new iridoids, jatadoids A and B, and two known compounds were isolated from Valeriana jatamansi and compounds 1 and 3 showed moderate neuroprotective effects against MPP+-induced neuronal cell death in human dopaminergic neuroblastoma SH-SY5Y cells.