Yuanming Li

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Alzheimer’s disease (AD) and vascular dementia (VaD) are the two most dominant forms of dementia in elderly people. Due to the large overlap between AD and VaD in clinical observations, great controversies exist regarding the distinction and connection between these two types of senile dementia. Here for the first time, we resort to the gene expression(More)
A three-component reaction of alkenes, aldehydes, and hydroperoxides catalyzed by FeCl(2) to β-peroxy ketones has been achieved. This three-component reaction can be also applied to the synthesis of α-carbonyl epoxides, through either a stepwise base-induced epoxidation of the separated β-peroxy ketone products or a one-pot process by simply adding base to(More)
OBJECTIVE To evaluate and analyze ovary cancer incidence and mortality in China in 2011 using ovary cancer data from population-based cancer registration in China, and to provide scientific information for its control and prevention. METHODS Invasive cases of ovary cancer were extracted and analyzed from the overall Chinese cancer database in 2011, which(More)
Unconventional couple: A new oxidative coupling protocol for amide bond formation has been developed (see scheme). The method provides an efficient and practical route for the synthesis of tertiary amides from readily available tertiary amines and aldehydes in the presence of a simple FeCl(2) catalyst. Mechanistic studies indicated that a peroxide and an(More)
Low response, treatment-related complications and relapse due to the low sensitivity of myelodysplastic syndrome (MDS) and leukemia stem cells (LSCs) or pre‑LSCs to arsenic trioxide (ATO), represent the main problems following treatment with ATO alone in patients with MDS. To solve these problems, a chemosensitization agent can be applied to increase the(More)
OBJECTIVE This study investigated the factors influencing survival time of patients with lung-cancer-associated hypercalcemia. DATA AND METHODS A total of 64 pathologically confirmed patients with Stage IV lung-cancer-associated hypercalcemia were enrolled from Beijing Hospitals between August 2010 and July 2015. Clinical materials included patients'(More)
USBKey is a new kind of intelligent security product that comprises microprocessor, memory chip and operation system. This paper proposes a software protection method that utilizes efficient calculation ability and security space of USBKey in multiuser environment, which combines multiple protection methods, identity authentication and trusted computing(More)
To systematically review early surgery and the optimal timing of surgery in patients with infective endocarditis (IE), a search for foreign and domestic articles on cohort studies about the association between early surgery and infective endocarditis published from inception to January 2015 was conducted in the PubMed, EMBASE, Chinese Biomedical Literature(More)
A novel and efficient approach to allyloxyamines by the allylation of nitrosoarenes with α-chiral allylboronates is described. C-O bond formation occurs with high stereospecificity and the product allyloxyamines are easily transformed into valuable chiral building blocks such as isoxazolidines and allylic alcohols. The reaction features complete(More)
An intermolecular oxidative cyclization between thiophenols and alkynes for benzothiophene formation has been established. A variety of multifunctional benzothiophenes are synthesized. In addition, we demonstrated that the obtained benzothiophenes can be used for further transformation to give diverse benzothiophene derivatives efficiently and selectively.