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Protein folding is critical for many biological processes. In this work, we propose an NoC-based multi-core platform for protein folding computation. We first identify the speedup bottleneck for applying conventional genetic algorithm on a mesh-based multi-core platform. Then, we address this computation- and communication- intensive problem while taking(More)
The astonishing rate of sensing modalities and data generation poses a tremendous impact on computing platforms for providing real-time mining and prediction capabilities. We are capable of monitoring thousands of genes and their interactions, but we lack efficient computing platforms for large-scale (exa-scale) data processing. Towards this end, we propose(More)
Cloud Computing is a promising approach to handle the growing needs for computation and storage in an efficient and cost-effective manner. Towards this end, characterizing workloads in the cloud infrastructure (e.g., a data center) is essential for performing cloud optimizations such as resource provisioning and energy minimization. However, there is a huge(More)
The continuous increase in integration densities contributed to a shift from Dennard's scaling to a parallelization era of multi-/many-core chips. However, for multicores to rapidly percolate the application domain from consumer multimedia to high-end functionality (e.g., security, healthcare, big data), power/energy and thermal efficiency challenges must(More)
The impact of dark silicon phenomenon on multicore processors under deeply-scaled FinFET technologies is investigated in this paper. To do this accurately, a cross-layer framework, spanning device, circuit, and architecture levels is initially introduced. Using this framework, leakage and dynamic power consumptions as well as frequency levels of in-order(More)
The complexity of the design-space exploration of large-scale NoCs is exacerbated not only by the ever-increasing number of cores, but also by the increased runtime uncertainties in both the scale and task structure of the emerging applications. Consequently, it is crucial to develop rigorous mathematical frameworks for capturing the task dependencies of(More)
This paper overviews the main computational issues in personalized and precision medicine (PPM), and present a cogent case for network-on-chip (NoC)-based multicore platforms as enablers in the process. We identify a series of challenges for the design and optimization of NoC-based solutions for PPM. To capture the characteristics of the cyber-physical(More)