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In this study, we present a novel low-frequency electrical stimulation paradigm for mesial temporal lobe epilepsy (MTLE). The paradigm utilizes the hippocampal commissure as a unique stimulation target to simultaneously influence large portions of the bilateral hippocampal network. When applied to an acute rat model of MTLE, animals that received(More)
Extracting physiological signals to control external devices such as prosthetics is a field of research that offers great hope for patients suffering from disabilities. In this paper, a novel source signal extraction algorithm, based on the source localization method Champagne, is presented. The algorithm constructs spatial filters that not only maximizes(More)
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