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- Koraljka Husnjak, Suzanne Elsasser, +7 authors Ivan Dikic
- Nature
- 2008
Proteasomal receptors that recognize ubiquitin chains attached to substrates are key mediators of selective protein degradation in eukaryotes. Here we report the identification of a new ubiquitin… (More)
- Tao Li, Junjie Xie, +10 authors Zhecheng Zhu
- Cancer research
- 2015
Despite progress in the diagnostics and treatment of hepatocellular carcinoma (HCC), its prognosis remains poor. In this study, we globally assessed long noncoding RNAs (lncRNA) for contributions to… (More)
- Wei Zhang, Yuan Shi, Yanzuo Chen, Jiang Ye, Xianyi Sha, Xiaoling Fang
- Biomaterials
- 2011
The aim of this study was to exploit the possibility of combination of active targeting function of folic acid by folate receptor-mediated endocytosis and overcoming multidrug resistance (MDR) by… (More)
- Wei Zhang, Yuan Shi, +5 authors Xiaoling Fang
- European journal of pharmaceutics and…
- 2010
The aim of this work was to demonstrate the advantage of using paclitaxel (PTX)-loaded Pluronic P123/F127 mixed micelles (PF-PTX) against non-small cell lung cancer (NSCLC) compared to Taxol.… (More)
- Yuan Shi, Xiang Chen, +13 authors Kylie J. Walters
- Science
- 2016
Hundreds of pathways for degradation converge at ubiquitin recognition by a proteasome. Here, we found that the five known proteasomal ubiquitin receptors in yeast are collectively nonessential for… (More)
- Byung-Hoon Lee, Ying Lu, +7 authors Daniel Finley
- Nature
- 2016
USP14 is a major regulator of the proteasome and one of three proteasome-associated deubiquitinating enzymes. Its effects on protein turnover are substrate-specific, for unknown reasons. We report… (More)
- Yuan Shi, Zachary Y Huang, Zhi Jiang Zeng, Zi Long Wang, Xiao Bo Wu, Wei Yan
- PloS one
- 2011
BACKGROUND
Young larvae of the honey bee (Apis mellifera) are totipotent; they can become either queens (reproductives) or workers (largely sterile helpers). DNA methylation has been shown to play an… (More)
- Yuan Shi, Wei Yan, Zachary Y Huang, Zi Long Wang, Xiao Bo Wu, Zhi Jiang Zeng
- Naturwissenschaften
- 2012
The honey bee is a social insect characterized by caste differentiation, by which a young larva can develop into either a queen or a worker. Despite possessing the same genome, queen and workers… (More)
- Ji Zhou, Geoff H. Werstuck, +8 authors Richard C. Austin
- FASEB journal : official publication of the…
- 2008
A causal relationship between diet-induced hyperhomocysteinemia (HHcy) and accelerated atherosclerosis has been established in apolipoprotein E-deficient (apoE(-/-)) mice. However, it is not known… (More)
- Jin-xiang Tan, Xiao-Yi Wang, +4 authors Guo-sheng Ren
- PloS one
- 2011
Hyaluronic acid (HA) is a component of the Extra-cellular matrix (ECM), it is closely correlated with tumor cell growth, proliferation, metastasis and angiogenesis, etc. Hyaluronidase (HAase) is a… (More)