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Cardiolipin remodeling by ALCAT1 links oxidative stress and mitochondrial dysfunction to obesity.
Oxidative stress causes mitochondrial dysfunction and metabolic complications through unknown mechanisms. Cardiolipin (CL) is a key mitochondrial phospholipid required for oxidative phosphorylation.Expand
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Penicillin-Binding Protein Transpeptidase Signatures for Tracking and Predicting β-Lactam Resistance Levels in Streptococcus pneumoniae
ABSTRACT β-Lactam antibiotics are the drugs of choice to treat pneumococcal infections. The spread of β-lactam-resistant pneumococci is a major concern in choosing an effective therapy for patients.Expand
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Outcome of Adenotonsillectomy for Obstructive Sleep Apnea Syndrome in Children
  • J. Ye, H. Liu, +4 authors Yuan Li
  • Medicine
  • The Annals of otology, rhinology, and laryngology
  • 1 August 2010
Objectives: We evaluated the outcome of adenotonsillectomy for obstructive sleep apnea syndrome (OSAS) in children using polysomnography (PSG) data and a quality-of-life (QOL) instrument. Methods: WeExpand
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MicroRNA-206 attenuates the growth and angiogenesis in non-small cell lung cancer cells by blocking the 14-3-3ζ/STAT3/HIF-1α/VEGF signaling
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality worldwide. Angiogenesis is the major hallmark in NSCLC. So, further elucidation of molecular mechanisms underlyingExpand
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The Protective Effect of Glycyrrhizic Acid on Renal Tubular Epithelial Cell Injury Induced by High Glucose
The aim of this study was to determine the beneficial effect of glycyrrhizic acid (GA) on type 2 diabetic nephropathy using renal tubular epithelial cell line (NRK-52E). The cells are divided intoExpand
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Rapid Inflammasome Activation following Mucosal SIV Infection of Rhesus Monkeys
The earliest events following mucosal HIV-1 infection, prior to measurable viremia, remain poorly understood. Here, by detailed necropsy studies, we show that the virus can rapidly disseminateExpand
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Glycoengineered Pichia produced anti-HER2 is comparable to trastuzumab in preclinical study
Mammalian cell culture systems are used predominantly for the production of therapeutic monoclonal antibody (mAb) products. A number of alternative platforms, such as Pichia engineered with aExpand
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Effects of biomass types and carbonization conditions on the chemical characteristics of hydrochars.
  • Xiaoyan Cao, K. Ro, +9 authors J. Mao
  • Chemistry, Medicine
  • Journal of agricultural and food chemistry
  • 20 September 2013
Effects of biomass types (bark mulch versus sugar beet pulp) and carbonization processing conditions (temperature, residence time, and phase of reaction medium) on the chemical characteristics ofExpand
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Total hip arthroplasty for active tuberculosis of the hip
Total hip arthroplasty (THA) has been used as a successful form of treatment in patients with long-standing tuberculosis, but it is unclear whether THA should be performed in patients with currentExpand
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A nonrandomized controlled study of sacral giant cell tumors with preoperative treatment of denosumab
Abstract The aim of this nonrandomized controlled study (level 3)was to evaluate whether preoperative denosumab treatment can reduce intraoperative blood loss, facilitate surgical treatment, andExpand
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