Yuan Jin

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A semiautomatic algorithm for segmenting organ surfaces from 3D medical images is presented in this work. The algorithm is based on a deformable model, and allows the user to initialize the model by combining and molding primitive shapes such as cylinders and spheres to form an initial approximate model of the organ surface. The initial model is(More)
The mechanisms by which sister chromatids maintain biorientation on the metaphase spindle are critical to the fidelity of chromosome segregation. Active force interplay exists between predominantly extensional microtubule-based spindle forces and restoring forces from chromatin. These forces regulate tension at the kinetochore that silences the spindle(More)
Permutation polynomials have been an interesting subject of study for a long time and have applications in many areas of mathematics and engineering. However, only a small number of specific classes of permutation polynomials are known so far. In this paper, six classes of linearized permutation polynomials and six classes of nonlinearized permutation(More)
BACKGROUND Chemokines and their receptors play important roles in host defense, organogenesis, hematopoiesis, and neuronal communication. Forty-two chemokines and 19 cognate receptors have been found in the human genome. Prior to this report, only 11 chicken chemokines and 7 receptors had been reported. The objectives of this study were to systematically(More)
Computational identification of transcription factor binding sites (TFBSs) is a rapid, cost-efficient way to locate unknown regulatory elements. With increased potential for high-throughput genome sequencing, the availability of accurate computational methods for TFBS prediction has never been as important as it currently is. To date, identifying TFBSs with(More)
Emerging evidence has showed that interleukin-18 (IL-8) promoter polymorphisms and plasma IL-18 levels may be associated with increased risk of periodontitis, but individually published results are inconclusive. The aim of this meta-analysis was to derive a more precise estimation of these associations. A literature search of PubMed, Cochrane Library,(More)
p55PIK, regulatory subunit of class IA phosphatidylinositol 3-kinase (PI3K), plays a crucial role in cell cycle progression by interaction with tumor repressor retinoblastoma (Rb) protein. A recent study showed that Rb protein can localize to the mitochondria in proliferative cells. Aberrant p55PIK expression may contribute to mitochondrial dysfunction in(More)
This paper investigates the e↵ect of real-time performance feedback and competition on the accuracy of crowd-workers for a document relevance assessment task. Through a series of controlled tests, we show that displaying a leaderboard to crowd-workers can motivate them to improve their performance, providing a bonus is o↵ered to the best performing workers.(More)
A multi-mode nonlinear constitutive model for mucus is constructed directly from micro- and macro-rheology experimental data on cell culture mucus, and a numerical algorithm is developed for the culture geometry and idealized cilia driving conditions. This study investigates the roles that mucus rheology, wall effects, and HBE culture geometry play in the(More)
Mirror self-recognition (MSR), i.e., the ability to recognize oneself in a mirror, is considered a potential index of self-recognition and the foundation of individual development. A wealth of literature on MSR is available for social animals, such as chimpanzees, Asian elephants and dolphins, yet little is known about MSR in solitary mammalian species. We(More)