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BACKGROUND The Dlc1 (deleted in liver cancer 1) tumour suppressor gene codes for a RhoGTPase activating protein that is found inactivated in many tumour types. Several transcriptional isoforms have been described but the functional significance and tissue distribution of each form is presently poorly understood. Also, differences in the number of isoforms(More)
Although the task of data record extraction from Web pages has been studied extensively, yet it fails to handle many pages due to their complexity in format or layout. In this paper, we propose a unified method to tackle this task by addressing several key issues in a uniform manner. A new search structure, named as Record Segmentation Tree (RST), is(More)
BACKGROUND Paramyosin is a thick myofibrillar protein found exclusively in invertebrates. Evidence suggested that paramyosin from helminths serves not only as a structural protein but also as an immunomodulatory agent. We previously reported that recombinant Trichinella spiralis paramyosin (Ts-Pmy) elicited a partial protective immunity in mice. In this(More)
Trichinellosis is an important foodborne zoonosis that is distributed worldwide. Trichinella spiralis may evade host complement-mediated attack by expressing complement inhibitory proteins, such as paramyosin (Pmy). Previous studies have shown that Trichinella spiralis paramyosin (Ts-Pmy) is able to bind to the human complement component C9 to inhibit the(More)
BACKGROUND Many evidences show the inverse correlation between helminth infection and allergic or autoimmune diseases. Identification and characterization of the active helminth-derived products responsible for the beneficial effects on allergic or inflammatory diseases will provide another feasible approach to treat these diseases. METHODS AND FINDINGS(More)
Trichinella spiralis expresses paramyosin (Ts-Pmy) not only as a structural protein but also as an immunomodulator that inhibits host complement as a survival strategy. Previous studies demonstrated that Ts-Pmy bound to complement components C8 and C9 and inhibited the polymerization of C9 during the formation of the membrane attack complex (MAC). The C9(More)
Trichinellosis is one of the most important food-borne parasitic zoonoses throughout the world. Because infected pigs are the major source of human infections, and China is becoming the largest international producer of pork, the development of a transmission-blocking vaccine to prevent swine from being infected is urgently needed for trichinellosis control(More)
This paper explores the use of ARIS for Semantic Web Service development. It proposes an ARIS-based transformation methodology for the automatic specification and development of Semantic Web Services. It also identifies research issues which have yet to be resolved for the development of a supporting software tool for the methodology.
There is a trend these days to add emotional characteristics as new features into human-computer interaction to equip machines with more intelligence when communicating with humans. Besides traditional audio-visual techniques, physiological signals provide a promising alternative for automatic emotion recognition. Ever since Dr. Picard and colleagues(More)